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What antignes are found on Class I on human chromosome 6
Loci: HLA-A, HLA-B, HLA-C
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What antignes are found on Class II on human chromosome 6
Loci: HLA-DR, HLA-DQ, HLA-DP
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What antignes are found on Class III on human chromosome 6
Loci: COMPLEMENT COMPONENTS
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Class I HLA antigens are found on mostly what?
Nucleated cells
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Class II HLA antigens are found on mostly what?
Bcells, activated T cells, macrophages, monocytes, and endothelial cells
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HLA demonstrate what (similar to that of the MNSs system)
demonstrate linkage disequlibrium
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What level should you phenotype at for Solid organs and tissue
Antigen level
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What level should you phenotype for stem cells
Allele level
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For solid organs HLA phenotyping is:
HLA-A, HLA-B, HLA-DR
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For stem cell HLA phenotyping is:
HLA-A, HLA-B, HLA-C, HLA-DR
(difference between stem cell and solid organ is: HLA-C)
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