-
Follicle-Stimulating Hormone (FSH)
- Anterior Pituitary
- Target Organ: Ovaries, Testes.
- Male: Sperm Production
- Female: Estrogen Secretion and growth of ovarian follicle.
-
Luteinizing Hormone ( LH )
- Anterior Pituitary
- Target: Ovaries, Testes
- Female: Ovlulation, maintenance of corpus luteum
- Male: Testosterone secretion
-
Thyroid-Stimulating Hormone ( TSH )
- Anterior Pituitary
- Target Organ: Thyroid Gland
- Growth of thyroid, secretion of thyroid hormone
-
Adrenocorticotropic hormone (ACTH)
- Anterior Pituitary
- Adrenal cortex
- Growth of adrenal cortex, secretion of glucocorticoids
-
Prolactin (PRL)
- Anterior Pituitary
- Mammary glands, testes
- Female: milk synthesis
- Male: increased LH sensitivity
-
Growth hormone (GH)
- Anterior Pituitary
- Liver, bone, cartilage, muscle, fat
- Widespread tissue growth, especially in the stated tissues
-
Antidiuretic hormone (ADH)
- Posterior Pituitary
- Kidneys
- Water retention
-
Oxytocin (OT)
- Posterior Pituitary
- Uterus, mammary glands
- Labor contractions, milk release; possibly involved in ejaculation, sperm transport, sexual affection, and mother–infant bonding
-
Melatonin
- Pineal gland
- Brain
- Uncertain; may influence mood and sexual maturation
-
Thymopoietin, thymosin, thymulin
- Thymus
- Immune cells (T lymphocytes)
- Stimulate T lymphocyte development and activity
-
Thyroxine (T4) and triiodothyronine (T3)
- Thyroid gland
- Most tissues
- Elevate metabolic rate and heat production; increase respiratory rate, heart rate, and strength of heartbeat; stimulate appetite and accelerate breakdown of nutrients; promote alertness and quicken reflexes; stimulate growth hormone secretion and growth of skin, hair, nails, teeth, and fetal nervous system
-
Calcitonin
- Thyroid gland
- Bone
- Stimulates bone deposition, mainly in children
-
Parathyroid hormone (PTH)
- Parathyroid glands
- Bone, kidneys, small intestine
- Raises blood Ca2+ level by stimulating bone resorption and inhibiting deposition, reducing urinary Ca2+ excretion, and enhancing calcitriol synthesis
-
Epinephrine, norepinephrine, dopamine
- Adrenal medulla
- Most tissues
- Promote alertness; mobilize organic fuels; raise metabolic rate; stimulate circulation and respiration; increase blood glucose level; inhibit insulin secretion and glucose uptake by insulin-dependent organs (sparing glucose for brain)
-
Aldosterone
- Adrenal cortex
- Kidney
- Promotes Na+ and water retention and K+ excretion; maintains blood pressure and volume
-
Cortisol and corticosterone
- Adrenal cortex
- Most tissues
- Stimulate fat and protein catabolism, gluconeogenesis, stress resistance, and tissue repair
-
Dehydroepiandrosterone
- Adrenal cortex
- Bone, muscle, integument, brain, many other tissues
- Precursor of testosterone; indirectly promotes growth of bones, pubic and axillary hair, apocrine glands, and fetal male reproductive tract; stimulates libido
-
Glucagon
- Pancreatic islets
- Primarily liver
- Stimulates amino acid absorption, gluconeogenesis, glycogen and fat breakdown; raises blood glucose and fatty acid levels
-
Insulin
- Pancreatic islets
- Most tissues
- Stimulates glucose and amino acid uptake; lowers blood glucose level; promotes glycogen, fat, and protein synthesis
-
Somatostatin
- Pancreatic islets
- Stomach, intestines, pancreatic islet cells
- Modulates digestion, nutrient absorption, and glucagon and insulin secretion
-
Pancreatic polypeptide
- Pancreatic islets
- Pancreas, gallbladder
- Inhibits release of bile and digestive enzymes
-
Gastrin
- Pancreatic islets
- Stomach
- Stimulates acid secretion and gastric motility
-
Estradiol
Stimulates female reproductive development and adolescent growth; regulates menstrual cycle and pregnancy; prepares mammary glands for lactation
-
Progesterone
- Ovaries
- Uterus, mammary glands
- Regulates menstrual cycle and pregnancy; prepares mammary glands for lactation
-
Inhibin
- Ovaries,Testes
- Anterior pituitary
- Inhibits FSH secretion
-
Testosterone
- Testes
- Many tissues
- Stimulates fetal and adolescent reproductive development, musculoskeletal growth, sperm production, and libido
-
Cholecalciferol
- Skin
- -
- Precursor of calcitriol (see kidneys)
-
Calcidiol
- Liver
- Precursor of calcitriol (see kidneys)
-
Angiotensinogen
- Liver
- Precursor of angiotensin II (see kidneys)
-
Erythropoietin
- Liver
- Red bone marrow
- Promotes red blood cell production, increases oxygen-carrying capacity of blood
-
Hepcidin
- Liver
- Small intestine, liver
- Promotes iron absorption and mobilization
-
Insulin-like growth factor I
- Liver
- Many tissues
- Prolongs and mediates action of growth hormone
-
Angiotensin I
- Kidneys
- Precursor of angiotensin II, a vasoconstrictor
-
Calcitriol
- Kidneys
- Small intestine
- Increases blood calcium level mainly by promoting intestinal absorption of Ca2+
-
Atrial natriuretic peptide and brain natriuretic peptide
- Heart
- Kidney
- Lower blood volume and pressure by promoting Na+ and water loss
-
Cholecystokinin
- Stomach and small intestine
- Gallbladder, brain
- Bile release; appetite suppression
-
Gastrin
- Stomach and small intestine
- Stomach
- Stimulates acid secretion
-
Ghrelin
- Stomach and small intestine
- Brain
- Stimulates hunger, initiates feeding
-
Stimulates hunger, initiates feeding
- Stomach and small intestine
- Brain
- Produces sense of satiety, terminates feeding
-
Leptin
- Adipose tissue
- Brain
- Limits appetite over long term
-
Osteocalcin
- Osseous tissue
- Pancreas, adipose tissue
- Stimulates pancreatic beta cells to multiply, increases insulin secretion, enhances insulin sensitivity of various tissues, and reduces fat deposition
-
Estrogen, progesterone
- Placenta
- Many tissues of mother and fetus
- Stimulate fetal development and maternal bodily adaptations to pregnancy; prepare mammary glands for lactation
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