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Some transport processes use transport proteins in the plasma membrane, but do not require ATP. This type of transport is known as...
Facilitated diffusion
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The majority of water molecules moving across plasma membranes by osmosis do so via a process that is most similar to...
Facilitated diffusion
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The sodium-postassium pump uses ATP to move sodium and postassium ions across the plasma membrane. This statement describes...
primary active transport
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A vesicle fuses with the plasma membrane and releases its contents to the extracellular fluid. This statement describes...
exocytosis
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A water filled passage that allows small molecules to pass through the membrane
channel proteins
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transports larger molecules by binding to the protein
carrier proteins
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Active transport of molecules require ATP because
the molecules are moved against their concentration gradients (uphill)
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The tonicity of a solution depends ONLY upon the...
concentration of nonpenetrating solutes
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The membrane potential of most cells
is negative, except when there is a change in the membrane permeability to ions
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Which body fluid compartment contains high levels of K+, large anions, and proteins?
intracellular fluid
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which body fluid compartment contains higher levels of Na+, Cl-, and HCO3-?
plasma and interstitial fluid
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bulk flow is fluid flow as a result of a ___ gradient.
pressure gradient
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what are the two extracellular fluid compartments in the body?
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The ion that plays a key role in initiating electrical signals in neurons is
Na+
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passive transport refers to a process that requires
no cellular energy
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Na+ ions are more concentrated in the extracellular fluid than in the intracellular fluid. This is an example of
chemical disequilibrium
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The inside of a resting cell is slightly negative relative to the outside. This is an example of
electrical disequilibrium
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Water will always move from ___ areas to ___ areas.
HYPOsmotic to HYPERosmotic
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membranes are selectively
permeable
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permeability is determined by
- size
- charge
- lipid solubility
- also: carriers & channels
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rate of diffusion is proportional to:
Surface area X concentration gradient X permeability
divided by: membrane thickness
Fick's Law
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movement of molecules from a region of high concentration to a region of low concentration due to the kinetic energy inherent in the molecules
diffusion
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diffusion that does not require input of energy
passive diffusion
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rate of diffusion is affected by:
- concentration gradient
- distance
- temperature
- molecular weight
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proteins embedded in the membrane that move molecules from one side to the other
mediated transport
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two types of transport proteins?
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water filled tubes that allow specific molecules to pass
channel transport proteins (open or gated)
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a transport protein that binds to the molecule then changes shape to carry it
carrier transport protein
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two types of cotransport proteins
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a cotransporter that carries two molecules in the same direction
symport
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a cotransporter that carries two molecules in opposite directions (NaK pump)
antiport
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transport channels that remain open
leak channels
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passive transport is also called
facilitated diffusion
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molecules moving against the concentration gradient and requires energy
active transport
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active transport requires
energy
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two types of active transport
- Primary active transport
- Secondary active transport
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Transport when ATP is directly activating a protein
Primary active transport
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Transport that uses the energy of a concentration gradient to pump another ion (not Na+) out of the cell
secondary active transport
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the interaction between the protein transporter and its ligand is specific
specificity
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molecules that have similar structure will compete with each other for binding to the transport protein
competition
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the transport protein can only accomodate so many molecules at a time - reaches max rate
saturation
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movement of a large molecule, whole organisms, or damaged cells
vesicular transport
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a type of endocytosis that creates a tunnel through a cell
potocytosis "caveolae"
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moving molecules out of cells, mostly proteins
exocytosis
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moving molecules in to cells
endocytosis
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the Na+K+pump is a type of _____ transport
primary active transport
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molarity is calculated by
molecular weight in grams/1 L
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osmolarity is the
molarity x number of particles per molecule
example: NaCl is 2 particles
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two solutions have the same osmolarity
isosmotic
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this solution has fewer dissolved particles than the other
hyposmotic
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this solution has more dissolved particles than the other
hyperosmotic
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the number of particles in a solution
osmolarity
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Compares the inside of the cell to the fluid outside the cell
tonicity
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this type of solute is not factored when considering tonicity
Penetrating solutes (PS)
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water does not move into or out of the cell
isotonic
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water will leave the cell
cell shrinks
hypertonic
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water will enter the cell
cell will swell
hypotonic
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charge distribution that creates disequilibrium is from the activity of
NaKATPase
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the separation of charges at unequal distribution across a membrane results in
electrical disequilibrium
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the difference between the outside and the inside of membranes mades the membrane
polarized
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if the difference in charge of the membrane increases it becomes
hyperpolarized
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if the difference in charge of the membrane decreases it becomes
depolarized
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