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Fear vs Anxiety
Fear: apprehension about what is known, usually rational
Anxiety: apprehension about unknown, irrational or excessive
Anxiety can be normal or clinical
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Physical Diseases that can present with anxiety
- -hyperthyroid
- -hypoglycemia
- -Cushings
- -Anemia
- -electrolyte imbalance
- -Mitral Valve Prolapse
- -cardiac arrhythmias
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Drugs that can present with anxiety
- Withdrawal from CNS depressants
- -alcohol
- -sedative hypnotics
- -antianxiety drugs
- CNS stimulant intoxication:
- -Amphetamines
- -Cocaine
- -Methylphenidate
- -Weight reducers
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Anxiety Disorders
1. Adjustment disorder with anxious features (normal after a stress)
2. Acute stress disorder
3. Generalized anxiety disorder
4. Agoraphobia
5. Panic Disorder (+/- agoraphobia)
6. Phobic Disorders (specific phobias, social phobias)
7. PTSD
8. OCD
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Natural History for anxiety disorders
- -lifetime prevalence 3%
- -1-2% annually with sx
- -women > men
- -onset by 30 years
-may fluctuate in severity but rarely disappear
-not a prodrome
-secondary depression is common
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Anxiety Disorder: Diagnosis
excessive anxiety and worry for more days than not for at least 6 months w/ 3+ of the following:
- -restlessness
- -increased fatigue
- -decreased concentration
- -irritability
- -muscle tension
- -sleep distrubance
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Agoraphobia
-anxiety about being in places or situations from which escape might be difficult or embarassing (outside home, crowd, line etc)
-avoids these situations
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Panic Disorder
- Recurrent unexpectant panic attacks followed by 1+ month of:
- -concern of another attack
- -worry about consequences
- -behaviour changes
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Panic Attack
- Discrete period of intense fear or discomfort
- -develop abruptly and peak within 10 minutes
- -comes on with a stressor
- with 4+ of the following:
- -palpitations
- -sweating
- -trembling
- -SOB
- -chest pain
- -nausea
- -dizzy
- -numbness or tingling
- -chills or hot flushes
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Social Phobia
-marked and persistent fear of scrutiny
-exposure to feared social situation provokes anxiety
-recognize that fear is unreasonable
- 1. Generalized (3% of pop)
- 2. Public Speaking (10% of pop)
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Post Traumatic Stress Disorder (PTSD)
-exposed to traumatic event (threatened death or serious injury)
-Reexperience: thoughts, dreams, recurring, cues
-Avoid Stimuli
-Persistent sx of increased arousal
-duration > 1 month
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Obsessive Compulsive Disorder
- Obsessions:
- -persistent thoughts, impulses
- -have insight
- -attempt to ignore but can't
- -cause anxiety
- Compulsions:
- -repetitive behaviours pt feels they need to perform in response to an obsession
- -rituals to reduce anxiety
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Treatment of Anxiety Disorders
- 1. rule out secondary causes
- 2. diganose major anxiety disorder
- 3. CBT
- 4. Relaxation, meditation, exercise
- 5. Behaviour therapies
- -Desensitization (phobia)
- -Forced immersion (phobia)
- -Thought-stopping (OCD)
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Pharmacotherpy
- 1. Antidepressants
- -SSRIs (may increase anxiety in the first wks)
- -response in 2-3 weeks
- -decrease panic and anxiety
- -sx reappear when drug is stopped
2. beta blockers
3. Benzos (not usually good)
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