Haematology2.txt

Home

Get App

Create

what is the inheritance of haemophilia A? which factor deficiency? which pathway?
- X linked recessive - so more men
- factor 8
- intrinsic pathway
what is haemophilia B otherwise known as?
- Christmas disease
- factor 9 deficiency
how do you treat haemophilia a?

replace F8 with recombinant F8
what are the symptoms of haemophilia?
- bleed into joints: haemarthrosis
- bleed into muscles: haematoma which lead to NERVE palsy and COMPARTMENT syndrome due to PRESSURE
how should vaccines be given to haemophiliacs?
- subcute
- never im as bleed!
what 2 tests are done for diagnosis of haemophilia? and results?
- increased APTT
- reduced factor
if someone has a warfarin allergy, what can they use instead?

phenindione: MOA vit K antagonist
which rash is assoc. with antiphospholipid syndrome?

livedo reticularis on legs
what is the treatment for A severe pulmonary embolism affecting a central pulmonary artery ?
- thrombolysis or even embolectomy
- emergency!! don't delay for imaging
what type of anaemia would you expect an epileptic on phenytoin to have? and why?
- megaloblastic anaemia
- phenytoid impairs folate metabolism: get functional folate deficiency
from a FBC, how would you differentiate an iron deficiency anaemia from thalassaemia?

in thalassaemia: inc red cell count
what is HbA2?

made of 2alpha and 2delta globins due to lack of beta globins in b-thalassaemia
which disorders can cause hypersegmented neutrophils?
- megaloblastic anaemia
- uraemia
- liver disease
when do target cells come apparent?
- iron deficiency
- haemolysis
- Hbopathies
- Liver disese

Author

kavinashah

19523

Card Set

Haematology2.txt

Description

haematol2

Updated

2010-05-16T23:13:46Z

Show Answers