antiplatelet drugs.txt

what is the MOA of aspirin?

stops conversion of AA into TXA2: to stop platelet aggregation
what is the MOA of clopidogrel?

inhibits ADP receptor: needed for platelet aggregation
what is the MOA of dipyradimole?

PDE inhibitor: therefore increasing cAMP in the cell which blocks the platelet response to ADP
what are the SE of aspirin?
- GI bleed
- perforate ulcer
- hyperuricaemia
- asthma
what is the antiplatelet regimen for stroke?
- aspirin 300mg initially
- 75mg daily lifelong
what is the antiplatelet regimen for TIA?
- aspirin 300mg initially
- 75mg daily lifelong
what is the antiplatelet regimen for unstable angina?
- aspirin 300mg initially
- 75mg daily lifelong
- +/- clopidogrel 300mg initially and 75mg daily lifelong
- iv GPIIb/IIIa blocker for high risk angioplasty or stent insertion
what is the antiplatelet regimen for post stent insertion?
- aspirin 75mg daily lifelong
- clopidogrel 75mg daily for 4 weeks
what is the antiplatelet regimen for AMI?
- aspirin 300mg initially
- 75mg daily lifelong

Author

kavinashah

19519

Card Set

antiplatelet drugs.txt

Description

antiplt

Updated

2010-05-16T23:10:13Z

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