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antiplatelet drugs.txt
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what is the MOA of aspirin?
stops conversion of AA into TXA2: to stop platelet aggregation
what is the MOA of clopidogrel?
inhibits ADP receptor: needed for platelet aggregation
what is the MOA of dipyradimole?
PDE inhibitor: therefore increasing cAMP in the cell which blocks the platelet response to ADP
what are the SE of aspirin?
GI bleed
perforate ulcer
hyperuricaemia
asthma
what is the antiplatelet regimen for stroke?
aspirin 300mg initially
75mg daily lifelong
what is the antiplatelet regimen for TIA?
aspirin 300mg initially
75mg daily lifelong
what is the antiplatelet regimen for unstable angina?
aspirin 300mg initially
75mg daily lifelong
+/- clopidogrel 300mg initially and 75mg daily lifelong
iv GPIIb/IIIa blocker for high risk angioplasty or stent insertion
what is the antiplatelet regimen for post stent insertion?
aspirin 75mg daily lifelong
clopidogrel 75mg daily for 4 weeks
what is the antiplatelet regimen for AMI?
aspirin 300mg initially
75mg daily lifelong
Author
kavinashah
ID
19519
Card Set
antiplatelet drugs.txt
Description
antiplt
Updated
2010-05-16T23:10:13Z
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