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Anatomy and Physiology
Studies the structure of the body parts along with their relationship to one another and concerns the function of the body, how the body parts work, and carry out there life-sustaining activities
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Homeostasis
The ability of the body to maintain a relativity constant internal environment regardless of the environment changes
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Organ system interrelationships
Organ systems cannot work in isolation; they work together cooperatively to promote the well being of the entire body
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Homeostatic imbalance
Most diseases can be regarded as a result of its disturbance
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Negative feedback mechanisms
The output shuts off the original stimulus or reduces its intensity
occurs in the opposite direction as the initial disturbance
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Positive Feedback mechanism
- The result or response enhances the original stimulus so that the activity is accelerated
- occurs in the same direction as the initial disturbance
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Anatomical position
- Body erect
- feet slightly apart
- palms facing forward
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Axial division
Makes up the main axis of our body, includes the head, neck, and trunk
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Appendicular division
Consists of the appendages or limbs which are attached to the body's axis
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Sagittal plane
A vertical plane that divides the body into left and right parts
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Midsagittal plane
line lies exactly in the midline
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Parasagittal plane
Offset from the midline
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Frontal plane
Lie vertically and divide the body into anterior or posterior
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Transverse plane
Runs horizontally from right to left dividing the body into superior or inferior
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Oblique plane
Any plane not parallel to the above 3 planes
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Distal
- Farther away from the origin
- only used for arms and legs
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Proximal
Close to the origin if body part
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Medial
Toward or at midline
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Lateral
Away from the midline
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Superficial
Forward or at the body surfaces
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Dorsal cavity
- Protects the fragile nervous system organs
- cranial cavity- encases the brain
- vertebral cavity- encloses the delicate spinal cord
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Ventral cavity
Houses visceral organs
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Thoracic cavity
- Surrounded by muscles and ribs
- Mediastinum-trachea, esophagus, and pericardial cavity (heart)
- pleural- lungs
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Abdominopelvic cavity
- Abdominal-stomach, intestines, and liver
- pelvic-bladder, rectum, and reproductive organs
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List the body cavities
Oral, nasal, orbital, synovial (joints in the neck), middle ear (ear drum)
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4 quadrants of the abdominopelvic regions
- Right upper quadrant (RUQ)
- left upper quadrant (LUQ)
- right lower quadrant (RLQ)
- left lower quadrant (LLQ)
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9 regions of the abdominolpelvic cavity
- Umbilical region
- epigastric region
- hypogastric region
- right & left iliac region
- right & left lumbar region
- right & left hypochondriac regions
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Merocrine glands
- Package their secretions into secretory vesicles and release secretion by exocytosis
- cell remains intact and not damaged
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Holocrine glands
- Cells accumulate their products within them until they rupture
- viscous mixture of both cell fragments and the product
- cells are constantly replaced
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Common characteristics of connective tissue
- They all arise from mesenchyme
- degrees of vascularity
- 3 basic components
- are separated by non living extracellular matrix
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Degrees of vasularity
- Cartilage is avascular
- dense connective tissue is poorly vascularized
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3 basic components of connective tissue
- Cells
- extracellular matrix (ECM)
- extracellular protein fibers
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Structural elements of CT
- Cells
- protein fibers
- ground substance
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4 main types of tissues
- Nervous
- muscle
- epithelial
- connective
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TissueTusks issue
Group of cells similar in structure or perform a common/similar function
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Epithelial tissue
Covers the body surfaces, lines the body cavities, and forms the majority of of glans
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Cellularity of epithelium
- Composed almost entirely of tightly packed cells
- connection between cells:
- desmosomes
- tight junctions
- gap junctions
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Desmosomes
- Anchoring junctions
- holds cells together in high stress
- abundant in tissues subjected to mechanical stress
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Tight junctions
- Forms an impermeable junction that encircles the cells
- prevents molecules from passing through extracellular space between adjacent cells
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Gap junctions
- Communicating junction between adjacent cells
- cells are chemically connected
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Polarity of epithelium
- Presence of structural and functional differences between the exposed and attached surfaces
- epithelium has an apical and basal surface
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Apical surface
Exposed either to the external environment or to some other internal body surface
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Basal surface
Lower side that attaches to the underlying connective tissue
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Epithelium attachment to a basement membrane
- Basal surface attached to the basement membrane
- noncellular, adhesive sheet that attaches the epithelium to the underlying connective tissues
- produced by the basal cells and CT
- forms a selective molecular barrier between epithelium and CT
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Avascular but innervated epithelium
- All epithelium lack blood vessels
- epithelium is richly innervated to detect changes in the environment
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Regeneration of epithelium
- Replacement of destroyed tissues with the same kind of tissues
- if and when their apical-basal polarity and lateral contacts are destroyed, they reproduce rapidly
- as long as they receive nutrition they will replace lost cells with cell division
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Functions of epithelium
- Main functions- forms boundaries between different environments
- other functions- protection, absorption, filtration, excretion, secretion, sensory reception
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Naming epithelium
Given 2 names... based on the number of layers present (simple, stratified) and the shape of the cells present (squamous, cubodial, or columnar)
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Simple epithelium
- Composed of a single cell layer
- all cells are in contact with the basement membrane
- found where stress is minimal
- functions: diffusion, absorption, secretion, and filtration
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Stratified epithelium
- Consist of two or more cell layers stacked on top of each other
- top layer is apical, lower layer is attached to the basement membrane
- common in high abrasion areas
- main functions: protection
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Squamos cells
- flat
- wide
- irregular in shape
- nucleus somewhat flattened
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Cubodial cells
- Tall as they are wide
- not perfect cubes, edges may be round
- nucleus is spherical and within the center of the cell
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Columnar cells
- Tall and column like
- nucleus is the oval and usually at the basal side of the cell
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GlandGland consists
Consists of one or more cells that make and secrete a particular product (secretion)
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What's the only unicellular gland?
A goblet cell which produces mucous
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How are glands classified?
- By the number of cells (unicellular, multicellular)
- site of product release (endocrine, exocrine)
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Endocrine glands
- Produce hormones
- secrete into the bloodstream
- all multicellular
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Exocrine glands
Composed of a duct and secretory unit, it secretes their products onto body surfaces (skin) or into body cavities
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