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Amitriptyline (Elavil)
TCAs for depression
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Imipramine (Tofranil)
TCA antidepressant.
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how do TCA's work?
Block the reuptake of NE and serotonin in the synaptic space.
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What the the 3 main side effects of TCAs
Orthostatic hypotension, Anticholinergic side effects, sedation
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Phenelzine (Nardil)
MAOI (monoamine oxidase inhibitor for depression) use for Depression. Block MAO in brain increasing NE, dopamine and serotonin.
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What type of foods should a person taking MAOIs avoid?
Tyramine- rich foods because they can lead to a HTN crisis.
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MAOIs are contraindicated in who?
Clients taking SSRIs and those in those with pheochromocytoma.
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Why are MAOI's such as Phenelzine (nardil) contraindicated in a person taking an SSRI?
because it can cause serotonin syndrome.
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What type of foods should be avoided when taking a MAOI such as Phenelzine (nardil)?
Tyramine-Rich foods because together can cause a HTN crisis.
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Bupropion HCL (Wellbutrin)
Atypical Antidepressant. Inhibits dopamine uptake.
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What are the theraputic uses of buproprion HCL (wellbutrin) a atypical antidepressant?
tx of depression, aid to quit smoking, and prevention of SAD (seasonal affective disorder)
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Floxetine (Prozac)
SSRI. Block reuptake of serotonin. Used for major depression.
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Effexor
SSRI- Major depressive disorder.
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What adverse effect can happen within 2-72 hours of taking an SSRI such as Prozac?
Serotonin syndrome. Symptoms: confusion, Fever, anxiety, agitation, tremors
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What is a adverse effect of SSRI's
serotonin syndrome, suicidal thoughts
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alprazolam (xanax)
Benzodiazepine used for anxiety.
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In order to avoid Lithium toxicity, what drugs should the client avoid while taking lithium?
NSAIDS. Concurent use w/ NSAIDS will increase renal reabsorption of lithium. leading to toxicity
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Risperidone (Risperdal)
Atypical Antipsychotics. Used for the tx of Schizophrenia
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What is a side effect of Risperidone (Risperdal)?
New onset of diabetes mellitus. Monitor for polyuria
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What is important to monitor patients for when taking lithium and a diuretic?
Signs and symptoms of Lithium toxicity because na is lost with diuretics.
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The nurse would avoid administering Bupropion (Wellbutrin) to a client who is @ risk what?
Seizures. If a client has suffered a head injury, would avoid because client is also @ risk for seizures
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Buspirone (BuSpar)
anxiolytic (nonbarbituate)
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What is important to inform the client about BuSpar?
the effects do not occur immediately.
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Paroxetine (Paxil)
SSRI antidepressant.
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What is the antidote for Benzodiazepine toxicity?
Flumazenil (Romazicon)
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What is a side effect that any SSRI can cause?
Bruxism
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Concurrent use of what drug can help tx Bruxism (Teeth grinding)?
Low-dose Buspirone
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A pt taking Phenelzine (Nardil) for depression should be monitored for what?
Orthostatic hypotension.
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Which type of antidepressant can cause sexual dysfunction side effects?
SSRIs
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What 3 major conditions can valporic acid cause?
Thrombocytopenia, pancreatitis or liver disease.
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Chlorpromazine (Thorazine)
Antipsychotic- Conventional (causes EPS symptoms)
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immediately during and after administration, pt's are @ risk for what when receiving Chlorpromazine (thorazine)?
hypotension
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Haloperidol (haldol)
Antipsychotic- High potency
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What is the advantage of taking atypical antipsychotic vs conventional psychotics?
There is less EPS symptoms with atypical antipsychotics
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Clozapine (Clozaril)
Atypical antipsychotic
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What is important to monitor for patients taking Clozapine (clozaril)
WBC count
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Atomextine (Strattera)
NSRI for ADHD.
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