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Chlorpheniramine
First generation H1 blocker
Cyproheptadine
First generation H1 blocker
Diphenhydramine
First generation H1 blocker
Hydroxyzine
First generation H1 blocker
Promethazine
First generation H1 blocker
Pyrilamine
First generation H1 blocker
Chlorpromazine
First generation H1 blocker
Cyclizine
First generation H1 blocker
Cyproheptadine - special mechanism
5-HT receptor blocker
Promethazine - special mechanism
alpha-adrenergic blocker
First generation H1 blocker
adverse effects
Strong sedation
ANS blocking activity
First generation H1 blocker
Uses
allergy reactions
decongestant
vomiting
sedation, hypnosis
What should be used with H1 blockers for decongestant
a1-adrenergic agonist
Fexofenadine
Second generation H1 blocker
Loratadine
Second generation H1 blocker
Cetirizine
Second generation H1 blocker
Azelastine
Second generation H1 blocker
Astemizole
Second generation H1 blocker
Terfenadine
Second generation H1 blocker
What is different between 2nd generation vs 1st generation H1 blockers
2nd generation is more specific
does not cross BBB
longer 1/2 life
what is unique adverse effect of Cetirizine
drowsiness (not commonly seen in 2nd generation H1 blockers)
Unique adverse effect of Astemizole & Terfenadine
long QT syndrome & arrhythmias (w/ CYP3A4 inhibitors)
Alprostadil
PGE1 analog
maintain ductus arteriosus
treat erectile dysfunction
Dinoprostone
PGE2 analog
cause abortion
induce labor
stop postpartum hemorrhage
Carboprost
PGF2a analog
cause abortion
Epoprostenol
PGI2
treat pulmonary hypertension
Misoprostol
PGE1 analog
prevent & treat gastric ulcer from NSAID
cause abortion
Latanoprost
PGF2a analog
treat glaucoma
Montelukast
Leukotriene receptor antagonist
Zafirlukast
Leukotriene receptor antagonist
Zileuton
Lipooxygenase inhibitor
Cromolyn sodium
mast cell stabilizers
Nedocromil
mast cell stabilizers
Olopatadine
mast cell stabilizers
specific for eye allergy
Author
xinchen3
ID
194837
Card Set
Autocoids
Description
drugs
Updated
2013-01-25T00:36:53Z
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