pharma

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quinidine(1a na block)
- 1.antiarrythmic.antimuscarinic,alpha blocker.
- 2.initial digitalisation required for AF
- 3.adv:cinchonism:tinnitus headache ocular G.I.dysfunction torsades.
- 4.displace digoxin frm tissuebindin sites
- hyperkalemia enchances effect
procainamide(1a na block)

antiarrythmic,hapten,metabolised by acetylization,binds to tissueproteins(SLE like syndrome),hematoxicity,torsades.
SLElike syndrome
- hydralazine
- isoniazid
- procanamide
- antihistones more specific
lidocaine(1b na block)
- post MI
- digoxin toxicity
- openheartsurgery
- advrse;;;seizures,least cardiotoxic
- always used i.v...so oral drugs in dis class are mexiletine,tocainide.
flecainide,propafenone(1c na block)
- last resort in refractory cases
- potent proarrythmic so not much used.

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194326

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pharma

Description

arryhtmia

Updated

2013-01-22T01:30:24Z

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