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Route of Epoetin alfa (Epogen/Procrit)
- IV
- Subcu
- 2000-40000 units 1-3 times a week
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MOA of Epoetin alfa (Epogen/Procrit)
Causes progenitor cells in bone marrow to make immature RBC & speeds up maturation
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Class of Epoetin alfa (Epogen/Procrit)
- Human recombinant hormone (erythropoietin) analogue
- antianemic
- Hematopoietic
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Indications of Epoetin alfa (Epogen/Procrit)
- Chenmo anemia
- Chronic renal failure anemia
- Zidovudine therapy(HIV)
- ↓ of need for blood transfusions in surgery
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Contraindications of Epoetin alfa (Epogen/Procrit)
- Allergy
- Uncontrolled HTN
- Hemoglobin ↑ 10-12gm/dL
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Adverse effects of Epoetin alfa (Epogen/Procrit)
- HTN, edema
- Anorexia N&V diarrhea
- Alopecia,rash
- Cough, dyspnea, sore throat
- Fever,blood dyscrasis, HA, bone pain
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What can occur if given to a pt w/hemoglobin above 10-12gm/dL
- Heart attack
- HF
- Stroke
- Death
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What can cause Epoetin alfa (Epogen/Procrit) to be ineffective
no iron storage in the body
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