Q2 Epoetin alfa (Epogen/Procrit)

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  1. Route of Epoetin alfa (Epogen/Procrit)
    • IV
    • Subcu
    • 2000-40000 units 1-3 times a week
  2. MOA of Epoetin alfa (Epogen/Procrit)
    Causes progenitor cells in bone marrow to make immature RBC & speeds up maturation
  3. Class of Epoetin alfa (Epogen/Procrit)
    • Human recombinant hormone (erythropoietin) analogue
    • antianemic
    • Hematopoietic
  4. Indications of Epoetin alfa (Epogen/Procrit)
    • Chenmo anemia
    • Chronic renal failure anemia
    • Zidovudine therapy(HIV)
    • ↓ of need for blood transfusions in surgery
  5. Contraindications of Epoetin alfa (Epogen/Procrit)
    • Allergy
    • Uncontrolled HTN
    • Hemoglobin ↑ 10-12gm/dL
  6. Adverse effects of Epoetin alfa (Epogen/Procrit)
    • HTN, edema
    • Anorexia N&V diarrhea
    • Alopecia,rash
    • Cough, dyspnea, sore throat
    • Fever,blood dyscrasis, HA, bone pain
  7. What can occur if given to a pt w/hemoglobin above 10-12gm/dL
    • Heart attack
    • HF
    • Stroke
    • Death
  8. What can cause Epoetin alfa (Epogen/Procrit) to be ineffective
    no iron storage in the body
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Q2 Epoetin alfa (Epogen/Procrit)
Q2 Epoetin alfa (Epogen/Procrit)
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