Q2 Heparin

Routes for Heparin
- IV-20,000-40,000 unit QD
- Subcu-5,000 units Q8-12 h(prophylaxis)
MOA of heparin

Binds to antithrombin III, which turns off three main activating factors which turns off coagulation pathway

factorII(thrombin) most sensitive to heparin
Class of heparin

Anticoagulant
Indications for heparin
- Thrmbosis/emolism
- DVT/PE prophylaxis
- clotting prevention
Contraindications of heparin
- Allergy
- Acute bleeding
- thrombocytopenia
Adverse effects of heparin
- Bleeding
- Hematoma
- Nausea
- Anemia
- Fever
- Edema
- HIT(heparin induced thrombocytopenia)
Interactions with heparin
- Lovenax
- NSAIDS
- Anticoagulants
- Thrombolytics
- Ceohlasporines
- Penicillin
When heparin is given IV what should be monitored

aPTT
What should you so if HIT II occurs

discontinue- may lead to paradoxical thrombosis
What are S&S of heparin overdose
- hematuria
- melena(stool blood)
- petechia
- ecchymosis
- bleeding gums
What can reverse the effects of heparin if overdose occurs
- protamine
- packed RBC

Author

tville01

193387

Card Set

Q2 Heparin

Description

Q2 Heparin

Updated

2013-01-17T14:32:18Z

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