Q2 Lovastatin (Mevacor)Atorvastatin(Lipitor) Simvastatin (Zocor)

  1. What is the med class for lovastation(Mevacor), atrovastatin ( Lipitor), and simvastatin (Aocor)
    • Antilipemic
    • HMG-CoA reductase inhibitor
  2. What are the indications for lovastatin, atrovastatin, and simvastatin
    • Types IIa/IIb Hyperlipidemia
    • Hypercholesterolemia
  3. How does Mevacor, Lipitor, and Zocor work
    Block the enzyme HMG-CoA which is needed to synthesize cholesterol in liver
  4. Which statin is the most effective to lower triglycerides
    atrovastatin(Lipitor)
  5. Contraindications of lovastatin(Mevacor), atrovastatin(Lipitor), simvastatin(Zocor)
    • Allergy
    • Pregnancy
    • Liver disease
    • Elevated liver enzymes
  6. Side effects of lovastatin(mevacor), atrovastatin(Lipitor), simvastatin(Zocor)
    • CNS-HA, dizzy, blurred vision, fatigue, nightmares,insomnia
    • GI-constipation, diarrhea, nausea, bowel changes, GI upset
    • Other-myalgias, rash, myopathy (rhabdomyolysis)
    • Renal damage
    • Elevation of liver enzyme(monitor)
  7. Interactions w/lovastatin(Mevacor), atrovastatin(Lipitor), simvastatin(Zocor)
    • Grapefruit juice
    • anticoagulants
    • Antilipemic
    • antidiabetic, insulin
    • Erythromiacin
    • Niacin
  8. How long for S&S to improve when taking lovastatin, atrovastatin, simvastatin
    6-8wks
  9. How does lovastatin(Mevacor) atrovastatin(Lipitor) and simvastastin(Zocor) effect cholesterol levels
    • ↓LDL 30-40%
    • ↑ HDL 2-15%
    • ↓Triglycerides 10-30%
  10. Which drug is the most effective at lowering triglycerides
    atrovastatin(Lipitor)
  11. What is the route for lovastatin(Mevacor), atrovastatin(Lipitor), and simvastatin(Zocor)
    PO
Author
tville01
ID
192940
Card Set
Q2 Lovastatin (Mevacor)Atorvastatin(Lipitor) Simvastatin (Zocor)
Description
Q2 Lovastatin (Mevacor)Atorvastatin (Lipitor)Simvastatin (Zocor)
Updated