"Soft tissue tumor, alveolar ridges of newborns, polypoid mass"
"Benign tumors of infancy, endothelial proliferation, circumscribed cellular mass of vascular endothelial cells, strawberry hemangioma (bright red, superficial), deeper hemangiomas are bluish due to Tyndall Effect"
"NO endothelial proliferation, Port Wine Stains (face, along CNV), excessive numbers of dilated blood vessels in the middle and deep dermis"
"Hamartomatous vascular proliferation involving tissues of brain and face, port wine stain or nevus flammeus, leptomenigial angiomas, gyriform �tramline� calcifications in the brain, glaucoma, vascular dilation of oral lesions, vascular hyperplasia of gums"
"Hamartomatous tumors of lymphathic vessels, dilated lymphatic vessels beneath the atrophic surface epithelium and in the deeper CT (Cavernous Lymphangioma), Cystic Hygroma, pebbly and vesicle apper."
"Benign tumor of smooth muscle, Masson Trichome stain shows SM bundles with normal collagen"
"Benign neoplasm of skeletal muscle, rounded and polygonal cells with focal vacuolization (spider web appearance) granular eosinophilic cytoplasm, PTAH=focal cross striations"
"Benign tumor of mature fat cells, yellow-nodular masses, sessile or pedunculated, thin fibrous capsule"
Osseus and Cartilagionous Choristomas
"Microscopically NORMAL tissue in an ABNORMAL location, bone and/or cartilage in the TONGUE, mass of dense lamellar bone beneath surface epithelium"
"Malignant tumor of fibroblasts, spindle-shaped cells with mild pleomorphism"
"Malignant tumor of smooth muscle origin, uterine wall and GI tract, RARE in oral cavity"
"Malignant tumor of skeletal muscle origin, infiltrative mass that grows rapidly, head and neck common"
Malignant Peripheral Nerve Sheath Tumor
50% of NF1 gene + people get this (Neurofibromatosis)
"Vascular neoplasm caused by HHV8 and KSHV, propensity in HIV+, lesion arises in endothelial cells"
Metastasis to Oral Soft Tissues
"Uncommon, Batson�s Plexus allows metastasis, gingiva and tongue most common, lung>kidney>melanoma>prostate>breast cancer for metastasis to oral cavity"
"Rupture of salivary gland duct due to local trauma, NEVER on upper lip, mucin-filled cyst-like (not a true cyst) cavity, granulation and foamy histiocytes present"
"Mucocele on the floor of the mouth, spilled mucin from sublingual gland"
Salivary Duct Cyst
"True cyst, �Mucous Retention Cyst�, lined by thin cuboidal epithelium, excretory gland duct lined by columnar epithelium, major and minor salivary glands"
"Calcified structures that develop within the salivary duct system, submandibular gland, radiopaque masses, concentric laminations around amorphous debris, squamous metaplasa of duct, �milk� stone out of duct with massage"
"Inflammation of salivary gland, due to bacteria, sialolithiasis, congential strictures; purulent exudates, chronic inflammatory infiltrate with associated acinar atrophy and ductal dilation and fibrosis"
"Non-inflammatory, salivary gland enlargement, parotid gland most common, hypertrophy of acinar cells, excessive accumulation of secretory granules "
"Excessive salivation, Water Brash, Drooling"
"Subjective dry mouth, usually due to medications in older people, saliva is ropey, thick or foamy, prone to dental caries and candidiasis"
"Chronic systemic autoimmune involving salivary and lacrimal gland dysfunction, Sicca Syndrome, Elevated IgG, RF, Anti-SS-A/B, lymphocytic infiltration of salivary glands, destruction of acinar cells, presence of focal chronic inflammatory aggregates"
Benign Lymphoepithelial Lesion
"Mikulicz disease, autoimmune disease, bilateral salivary and lacrimal enlargmenet, lymphocytic infiltration of the parotid gland with associated epimyoepithelial island"
"Local inflammatory destruction of salivary glands, palatal salivary glands most common, necrotic mucous acini and adjacent ductal squamous metaplasia, ulceration in later stages, will heal on its own"
"Mixture of ductal and myoepithelial elements, parotid gland most common, well-circumscribed, encapsulated, benign tumor with variable microscopic pattern and mesenchyme-like background, fat or osteoid can be present"
"Transformation of ductal and acinar cells to oncocytes, proliferation and accumulation of oncocytes in salivary glands, polyhedral, granular eosinophilic cytoplasm (result of proliferation of mitochondria)"
"Monomorphic Adenoma, composed of large epithelial cells (oncocytes), well-circumscribed, benign, abundant granular, eosinophilic cytoplasm (mitochondria)"
"Benign, monomorphic adenoma, parotid gland tumor, associated with smoking, bilateral (but not at same time), 2 layers: inner luminal layer with tall columnar cells, palasading, centrally placed nuclei, second layer of cuboidal or polygonal cells with more vesicular nuclei, papillary infoldings that protrude into cystic spaces "
(Papillary Cystadenoma Lymphomatosum)
"Monomorphic Adenoma, minor salivary glands, upper lip, uniform columnar cells forming canal-like ductal structures with deeply basophilic nuclei"
Basal Cell Adenoma
"Monomorphic Adenoma, Benign, parotid gland, encapsulated or well-circumscribed, cords of basaloid cells arranged in a trabecular pattern"
"Malignant, parotid gland, mixture of mucus-producing cells and squamous (epithelial cells), intermediate cells (progenitor cells), solid islands of squamous and intermediate cells, pleomorphism and mitotic activity (High-Grade Tumor)"
Intraosseous Mucoepidermoid Carcinoma
"Malignant, salivary gland tumor within the jaw (intrabony), associated with impacted teeth or dentigerous cysts, prominent cyst formation, minimal cellular atypia, high proportion of mucous cells (Low-Grade Tumor)"
Acinic Cell Adenocarcinoma
"Malignant, serous acinar differentiation"
Malignant Mixed Tumors
"Malignant counterpart to benign mixed tumor or pleomorphic adenoma, �carcinoma ex pleomorphic adenoma� (Epithelial cells�malignant), areas of malignant degeneration of epithelial cells, cellular pleomorphism and abnormal mitotic activity"
Adenoid Cystic Carcinoma
"Malignant, submandibular gland, mixture of myoepithelial cells and ductal cells; Three histo patterns: Cribriform, tubular, solid; perineural invasion (not pathognomonic)�pain due to cells around nerve bundle, bad prognosis over time"
Polymorphous Low-Grad Adenocarcinoma
"Malignant, Minor salivary glands, Cribriform pattern mimics adenoid cystic carcinoma, perineural invasion common, good prognosis"