the degree of which the pt blood coaguability has been reduced by the drug
What should be avoided when on warfarin(Coumadin)
Foods high in vitamin K(may decrease medication ability to prevent clots)
Contraindications of warfarin(Coumadin)
pregnancy
Risk/actual acute bleeding
Adverse effects of warfarin(Coumadin)
bleeding
Teratogenicity (bone malformations in a fetus occuring from dysfunctional calcium usage)
Skin necrosis if warfarin is not carefully initiated (procoagulable state in the first few days of therapy as functioning clotting factors are used up)
MOA of warfarin(Coumadin)
Warfarin is a vitamin K analog, and competitively inhibits vitamin K reductase which inhibition formation of factors II, VII, IX, X, proteins C and S