-
Hydroxazine
Anti-Anxiety
- Vistaril
- Anticholinergic
- Non-Controlled
- Sedating
-
Buspirone
Anti-Anxiety
- Buspar
- Well Tolerated
- Delayed Onset of Action
-
Flumazenil
Benzo Overdose
Romazicon
-
-
-
-
Loxapine
Schizo
- Loxitane
- Few Side effects
- Dose 10-80mg
- MAX 250
-
Clozapine
Schizo
- Clozaril/FazaClo
- SGA
- Start 12.5-25mg QD, increase 25-50mg day
- Target- 300mg
- TITRATE
- Monitor CBC Weekly/Bi-weekly/Q 4weeks (6 month interval)
- Contra: Smoking, Benzo, TCA
Agranulocytosis, Seizures, Myocarditis, Resp Dep
-
Olanzapine
Schizo
- Zyprexa
- Psychotic dose- 5-10mg
- Manic dose- 10-15mg
- Post Injection Delirium
- Relprevv- Long acting IM.
- Oral Target Dose
- 10 210/2:405/4::150/2:300/4
- 15 300/2::210/2 405/4
- 20 300/2-
-
Risperidone
Schizo/Bipolar
- Risperdal
- 1mg BID increase 1-2mg/week
- Interacts with HTN meds
- #1
-
Paliperidone
Schizo
- Invega
- Active Metabolite of Risperidone
-
Quentapine
Schizo
- Seroquel
- XR version adjunctive for depression
- Best effect at 600-800mg day
- Sedating
-
Ziprasidone
Schizo
- Geodon
- Initial dose 20mg BID WITH FOOD
- Cardiovascular Issues
- Obtain baseline EKG and K/Ca/Mg levels
-
Aripiprazole
Schizo
- Abilify
- Adjunctive for depression
-
Asenapine
Schizo
- Saphris
- Acute disorder/Mixed mania
- Sublingual
- 5mg BID Schizo
- 10mg BID Manic
-
Lurasidone
Schizo
- Acute
- 40mg-80mg QD
- Few Side effects
- 40-80mg/day
- Contra with renal impairment
-
-
-
Zolpidem
Sleep
- Ambien/Zolpmist
- All short term except CR
-
-
Eszopiclone
Sleep
- Lunesta
- For long term use.
- Copper Taste
-
-
Lithium
Bipolar
- Eskalith/Lithobid
- Mood Stabilizer
- Interacts with ACE/ARB/NSAID/Diuretics
- Toxicity causes tremors and memory issues
- Pregnancy D
-
Valproate
Bipolar
- Depakote, Depa-
- Anticonvulsant
- First choice combined with lithium for rapid cycling
- 500-750mg/day max 60mg/kg/day
- Serum concentration between 60 and 125mcg/ml
- 200mcg=toxicity
- Minor increase in LFTs
- Pancreatitis
-
Carbamazepine
Bipolar
- Carbatrol, Tegretol, Equetro
- Second option
-
Lamitrogine
Bipolar
- Lamictal
- Maintenance therapy
-
Phenelzine
Depression
- Nardil
- MAOI
- Dietary Restrictions
-
Depression MAOIs
- Postural Hypotension
- Diarrhea
- Headache
- Sexual Dysfunction
- Sedation
- Insomnia
- Lethal Overdose
-
Tricyclic Antidepressants
- Inhibits S and NE reuptake
- Sedation
- Anticholinergic ADRs
- Sexual Dysfunction
- Lethal Overdose
- INEXPENSIVE, Efficacious.
-
-
SSRIs
- Efficacious
- Safe in overdose
- once weekly formulations
- Sexual disfunction
- drug drug interactions
- Withdrawal symptoms
-
-
-
-
-
-
-
SNRIs
- Not sedating
- Increase BP
- Safe with overdose.
- Few drug interactions except duloxetine
-
Desvenlafaxine
Depression
SNRI
-
Duloxetine
Depression
SNRI
-
Venlafaxine
Depression
SNRI
-
Nefazodone
Depression
- Serzone
- Triazalopyridine
- 100mg BID
-
Trazodone
Depression
- Desyrel, Oleptro
- Triazolopyridine
- 150mg/day
-
Triazolopyridines
- Expensive
- No sexual Disfunction
- Safe in overdose
- No withdrawal
-
Mirtazapine
Depression
- Remeron
- Tetracyclic
- Almost no side effects besides weight gain and sedation
-
Buproprion
Depression
- Wellbutrin
- Causes insomnia
- Treats smoking
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