Micro Test 3: Fun Facts

  1. E. coli antigens under genetic control
    K and H
  2. Phase variation protects E. coli from
    Ab-mediated cell death
  3. Present in 75% of E. coli neonatal meningitis
    K1 capsular antigen
  4. EPEC fimbriae
  5. Ipa found in pathogenesis of
    EIEC and Shigella
  6. CFA main virulence factor in
  7. Liver abscesses in alcoholics
  8. NDM-1
    • Found in Klebsiella
    • Causes resistance to B-lactams
  9. Forms biofilms on catheters
  10. Lactose-N, swarming motility, Urease-P
  11. HA-neonatal sepsis, better to use single dose of antibiotics rather than multiple doses
    E. cloaceae
  12. Contact lens induced acute red eye
  13. Only one of the species that can grow without salt
    V. cholerae
  14. Vibrios that produce a capsule
    V. vulnificus and non-O1 V. cholerae
  15. 2 circular chromosomes, that are each essential
    V. cholerae and V. vulnificus
  16. O1 V. choleraes that can shift between each other?

    What is the other one?
    Inaba, Ogawa

    Hikojima, transitional form of cholera

    Inaba <-> Hikojima <-> Ogawa
  17. Pica
  18. Unilateral blindness from worm
    Ocular Larval Migrans (form of VLM)
  19. Produces H2S
  20. Charcot-leydeon crystals in stool
    Whipwom (trichus trichuria)
  21. Microcytic anemia
    • Hookworms
    • Whipworms
  22. Megaloblastic anemia
    Diphylobatum latum
  23. Head curved opposite to curvature of body
  24. Loeffler's Syndrome (pulmonary infiltrates, peripheral eosinophilia)
    CLM, Hookworms, Ascaris lumbricoides
  25. Autoinfection due to rhabditiform larvae
    Strongloides sterocoralis
  26. Striated skeletal muscle
    Trichinella spiralis
  27. 2 Phases of Trichinella spiralis.  Which one is inhabited in skeletal muscle.
    • Enteral
    • Parenteral (skeletal muscle)
  28. Chyluria
  29. 2 Phases of Filariasis
    • Acute Inflammatory Disease:  No genital involvement
    • Chronic Inflammatory Disease:  Eephantitis, recurrent orchitis
  30. Ivermectin can't be used by itselfs to treat filariasis because?
    It doesn't kill adults
  31. African river blind sickness
  32. Snow flake corneal opacities
    Onchocercera volvulus

    Also gives hanging groin and subcutaneous nodeuls
  33. Intense pruritic rxn w/ erythema, edema, and papules upon microfilaria death
    Mazzotti rxn (Onchocerca volvulus)
  34. Coin lesions
  35. Do NOT reach maturity in humans are no microfilaria are seen in blood
    Dirofilaria immitis and tenuis (dog and racoon heartworm, respectively)
  36. Beef tapeworm
    Taenia saginta
  37. Pork tapeworm
    Taenia solium
  38. Unarmed scolex w/ 4 suckers
    Gravid proglottid has 15-30 uterine branches
    No hooks
    Taenia saginta
  39. Scolex has 4 suckers and armed rostellum
    Gravid proglottids have 7-12 branches
    Double row of 22-32 hooks
    T. solium
  40. Fluid-filled bladder worm with an inverted scolex, causes CNS cysts
  41. Ingestion of fleas containing infectie cysticerci, conical rostellum
    Diplidium caninum
  42. Hydatid cysts
    Echinococcus granulosus
  43. Ingesting imporperly cooked fish w/ infective plerocercoid larvae in their tissues --> megaloblastic anemia, humans are definitive hosts
    Diphyllobothrium latum
  44. Small Intestine Flukes
    • F. buski
    • Heterophyes heterophyes
    • Metagonium yokogawei
  45. Liver flukes
    • F. hepatica
    • Clonorchis schinensis
  46. Lung flukes
    P. westermani
  47. Blood flukes
  48. Eosinophilia
    Prominent in flukes
  49. Protozoa w/ eosinophilia
    Isospora belli
  50. Halzoun
    Eating raw sheep liver --> Fasciola hepatica
  51. Jaundice is a symptom of which fluke?
    Clonorchis sinensis
  52. S. mansoni, which veins
    Colonic mesenteric veins
  53. S. japonicum
    Small intestine
  54. S. haematobium
    Vesicle, prostatic and urinary plexus
  55. Adults are diecious (NOT hermaphroditic like other trematodes)
  56. Only schistosome where humans are the primary reservoir
    S. haemotobium
  57. Pipe stem fibrosis
    Schistosoma mansoni
  58. Yangtze River Fever
    Schistosoma japonicum
  59. Schistosome that causes hematuria
    Schistosoma haematobium
  60. Swimmer's Itch
    Bird schistome (Do NoT mature in abnormal host)
  61. Encodes genes for the 2 subunits of cholera toxin in V. cholerae (ctxA and ctxB)
    Bacteriophage CTXφ
  62. V. parahaemolyticus hemolysis?
    B- hemolysis
  63. Most common cause of GI disease in Japan, most common Vibrio species causing GI disease in US
    V. parahemolyticus
  64. Rice-water stool
  65. Raw oysters
  66. Selective agar for Vibrio
    Thiosufate citrate bile salts sucrose (TCBS)
  67. GI infection w/ campylobacter jejuni is linked w/ development of
    Guillian-Barre Syndrome
  68. Oxidase-P, Urease-P (NH3 raises pH, protect bacteria)
    H. pylori
  69. Binds to MHC II cells and causes apoptosis
    H. pylori
  70. Produces fluorescein and pyocyanin
  71. Chelates iron, green
  72. O2 --> O2-, blue
  73. Induces IL-17 response
    PopB protein (Psuedomonas)
  74. GM1 triggers
    IL-8 (Pseudomonas)
  75. Exotoxin A:
    Produced by
    Activated  by
    Enzymatically ribosylates
    • Pseudomonas
    • furin
    • EF2
  76. Dented cans, home canned vegetables, home smoked meats
    C. botulism
  77. Virulence factor of pseudomonas that ribosylates EF2
    Exotoxin A
  78. What favors Exotoxin A production by pseudomonas?
    Low iron content
  79. Inhibits LasR of Pseudomonas
  80. Pseudomonas protease capable of inducing inflammation
  81. Pseudomonas destroys (4 parts of immune system)
    • Complement
    • Opsonization
    • Ab
    • Cytokine rxns

    (Can Completely Obliterate Abs)
  82. Pseudomonas is #1 cause infections
    • Burn infections
    • Lower respiratory infections (Mycoplasma does URI)
    • Otitis externa
  83. All Pseudomonas infections lead to bactermia except ofr
    Chronic Infections (CF pts)
  84. Cable Pili
    Burkholderia cepacia (infects CF pts.)
  85. Secretes B-lactamases to protect other bacteria
    Strenotrophomonas maltophilia
  86. Neisseria meningitidis agar
    • Chocolate agar
    • Thayer-Martin Agar
  87. ABCYW in polysaccharide capsules
    N. meningitidis
  88. IgG and IgA1 abs directed against this interfere w/ bactericidal action of abs directed against LOS
    RMF Protein (N. meningitidis)
  89. N. meningitidis:  What type of vaccine
  90. Exacerbates COPD
    Moraxella catarrhalis
  91. Septic arthritis in children
    Kingella kingae
  92. Fermentation
    Substrate level phosphorylation
  93. Anaerobic respiration
    Oxidative phosphorylation (creates proton gradient)
  94. C. dificille toxin:  Enterotoxin, chemotactic for neutrophils
    Toxin A
  95. C. dificile toxin:  Cytotoxin, kills intestinal epithelial cell
    Toxin B
  96. C. dificile strain no always associated w/ antibiotic use
  97. What strain of C. perfringens does food poisoning
  98. What strain of C. perfringens does necrotizing enteritis?
    Type C strains
  99. Drum stick shape
    Clostridium tetani
  100. Inhibited by serum cholesterol
  101. Gynecologic toxic shock syndrome associated with post partum and post abortion women
    Clostridium sordelli
  102. Sulfur granules, lumpy jaw
  103. Legionella pneumophila media
    Charcoal yeast agar
  104. Produces inhibitor of oxidative burst
    Legionella pneumophilia
  105. Iraqi war veterans
    Acinetobacter baumanni
  106. MDRAB
    Acinetobacter baumanni (not acquired as a single element)
  107. Neutrophils protect lungs from
    A. baumannii
  108. Cellular casts are indicative of
  109. Contaminated milk products (goat cheese)
    Brucella mellitensis
  110. Drenching sweats, focal lesions in bones, joints and urinary tract
  111. Francisella tularensis media
    Cysteine blood agar (hold plates for 3 weeks)
  112. Ulceroglandular
    Francisella tularensis
  113. Rabbit paws/meat
    Francisella tularensis
  114. Bipolar staining (safety pins)
  115. Cat Scratch Disease
    Bartonella henselae
  116. Resembles Kapsoi's sarcoma but w/ subacute endocarditis
    Atypical CSD (B. henselae)
Card Set
Micro Test 3: Fun Facts
Fun facts