Aspirin

Platelet inhibitor, anti-inflammatory agent

• Prostaglandin inhibition
• prostaglandins; a group of lipids that act as chemical messengers.

New onset chest pain suggestive of acute myocardial infarction. Signs and symptoms suggestive of recent cerebrovascular accident.

Hypersensitivity. Relatively contraindicated in patients with active ulcer disease or asthma.

Heartburn, GI Bleeding, prolonged bleeding, nausea and vomitting. Wheezing in allergic reactions.

use with caution in pts allergic to NSAIDs.

81mg, 160mg, 325mg

160mg to 325mg PO (chewed if possible)

• onset: 30-45 minutes
• Peak effect: variable
• Duration: variable

• Pregnancy safety: category D
• Not recommended in pediatric pts.