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PAD-Med treatment Hyperlipidemia
- Statins (LIpitor, Zocor, Mevacor, Pravachol)
- Bile acid sequestrants (Questran, Prevalite, Niacor, Niaspan)
- Cholesterol absorption inhibitors (Zetia)
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PAD-Med Treatment
- Antiplaetelt agents (Aspirin, Plavix)
- ACE Inhibitors ('pril)
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PAD-Med Treatment Intermittent Claudication
- Pentoxifylline (Trental)
- -increase RBC flexibility
- -decrease blood viscoisty (more liquid)
- Cilostazol (Pletal)
- -increase vasodilation
- -decrease platelet aggregation
- -increase walking distance
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DVT-Medical Mgmt
- Unfractionated heparin
- Low-moelcular weght heparin-enoxaprin (Lovonox)
- Thrombolytic therapy-used to dissolve clot
- Factor Xa inhibitors-Arixtra
- Oral Anticoagulant-warfarin (Coumadin) Vitamin K antagonists
-
Unfractionated-Heparin
- delays clotting time
- prevents thrombus formation
- aPtt-therapeutic level 1.5-2.5 x normal control
- Monitored q 4-6 hour range 46-70 seconds
- D/C > 90.1-100 sec heparin
- Antidote-Protamine sulfate, w/ 1mg revering 100 units
- Complication: HITT--> D/C use Argatroban or lepirudin
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Low molecular weight Lovenox or Fragmin
- safe for use in pregnancy
- costs more than heparin
- longer half life
- routine coagulatino tests not required
- DO NOT expel air bubble
-
Warfarin sodium (Coumadin)
- given orally same time each day
- PT 1.5-2 x normal with goal 24 sec
- normal PT 8.8-11.6 sec
- INR normal 1-2
- anticoagulation level 2-3
- Antidote Vitamin K (Mephyton)
- Therapy contd 3-6 or more months
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Raynaud's Disease-Medical Mgmt
- Calcium Channel Blockers: first-ling drug tx
- Nifedipine (Procardia)
- Diltiazem (Cardizem)
- Adverse effects:
- tachycardia, HA, flushing, dizziness, peripheral edema
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Valve Disorder-Medical Mgmt
- Digitalis
- Diuretics
- Antidysrhythics (B-Blockers, calcium-channel blockers, ACE inhibitors)
- Anticoagulants
- Prophylactic antibiotic
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Rheumatic Fever-Med mgmt
- Antibiotic therapy (monthing injection or orally daily)
- Salicylates (ASA) for fever and joint pain
- Corticosteriods for wever caridtis
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Infective Endocarditis-Med mgmt
- Antibiotic therapy IV for 2-6 weeks based on cultures
- ASA
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Myocarditis-Med mgmt
- Antibiotics
- Antiviral therapy with interferon-a
- Corticosteriods
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Acute Pericarditi-Med mgmt
- Antibiotics
- NSAIDS ro high-dose ASA
- Corticosteroids
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