-
Adult water weight
55-60%
-
ECF
- extracellular fluid
- in veins-arteries-epethelial cells
- Interstitial
- Intravascular
- Transcellular
-
Functions of body fluid
- medium for transport
- needed for cellular metabolism
- solvent for electrolytes
- helps digestion
- acts as lubricant
-
D5 normal solution
hypotonic
-
Specific gravity of water??
1
-
Fluid
water that contains dissolved and suspended substances glycose, mineral salts, proteins
-
Isotonic
- 285-315
- Blood is isotonic
- goes in vein and stays in isotonic blood
-
Fluid concentration
Osmolaity
-
Normal pH of body
7.35-7.45
-
Albumin controls
- osmotic pressure shift
- shifting always in equal amounts
-
Ions
- charged particles (electrolytes)
- Cation=Na, K,Ca,Mg
- Ation=Cl, HCO3, SO4
(HCO3=biocarbonate)
-
Biocarbonate
pH buffer in body
-
Fluid distribution
movement of fluid amoung compartments ICF, ECF, interestitial, and vascular
-
Fluid output
- Influenced by Antidiuretic Hormone (ADH)
- produced by pituitary gland
- Renin-angiotensin-aldosterone system (RAAS)
- produced by kidney & adrenal gland
- Atrial natriuretic peptides (ANP's)
- stimulates heart
-
Hypothalamus
triggers thirst sensation
-
Pituitary regulation
- releases ADH (antidiuretic hormone)
- in response to serum osmolarity
-
Renal regulation
- Nephron receptors sense decrease pressure and kidney secretes renin---tells body to hold on to fluid
- Angiotensin 1 & 11
-
Angiotensin II
- causes Na and H2O retension by kindey
- stimulates adrenal cortex to secrete aldosterone which causes kindey to exrete K and Na and H2O
-
Hypovolemia
- low volume high concentration
- diaharia, vomiting, shock, hemorage
-
Hypernatremia
- to much sodium in plasma
- effect neuro function
- water deficit
-
Hypnatremia
- to little sodium in plasma
- to much water
-
Osmolality imbalance
- hypernatremia
- hyponatremia
-
Clinical dehydrations
ECV deficit and hypernatremia combined
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