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Graphic Objective 3.
Linst and classify the components of the plasma membrane. as defined by the fluid-mosaic model.Cassify membreane proteins as peripheral or interal.
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Define permeability
tells how easily a substance can cross the plasma membrane.
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What is differential permeability
is what defines a cell.
-the cell lets some things pass (water and cell nutrients must be allowed into the cell)
-the cell does not let other things pass(guts of the cell should not leak out)(toxic substances should not leak in)
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What can pass through the cell membrane?
Small uncharged moleculeslipid-soluble substances (fat-soluble)gases
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What can't pass through the cell membrane?
charged ionswater-soluble molecules
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Only ______ and ________ can move across the cell membrane without help.
Water; Gases
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The random motion of small particles or even molecules in a liquid or gas is called
Brownian motion
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Physical principles underlying diffusion.
Molecules in a gas or liquid can move around.
The warmer the tempertature, the more movement.
The smaller the molecule, the more movement.
This random movement is seen as diffusion: over time, the concentration of the substance will become equal in all parts of the system.
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Graphic objective 13 module 4
Discuss the physical principles underlying osmosis
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Passive Transport
No energy needed
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Facitlitated diffusion
protein channels or carriers in the cell membrane facilitate the diffusion of substances.
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What has to be escorted, even if the concentration is higher outside than inside.
Larger and charged molecules
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What are the critical steps in the facilitated diffusion of glucose?
Step 1: Gluscose fits into "pocket" of glucose transporter.
Step 2: Protein changes shape, closing glucose pocket.
Step 3: Glucose transporter changes shape again, forces glucose into cytoplasm.
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What is Active Transport?
Requires energy. Is used to move an ion against its concentration gradient.
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Energy sources for active transport?
ATP
Pre-existing storage of energy in a concentration gradient.
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When molecules are moved against their concentration gradient (from low concentration to high), energy is required.
Active Transport
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Na+ is _______ outside, ________ inside.
high; low
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K+ is _______ outside, _________ inside.
low; high
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Na+/K+ pump moves both
against their concentration gradients (Na+ moves out, K+ moves in), splits ATP for energy to do this (ATPase).
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Three Na+ ions rest in a pocket of the pump. Thes Na+ ions are expelled as _______ is split into ____ + _______, releasing the nergy needed to drive the pump. Then, two K+ ions _______ outside the cell and these are ________ inside the cell.
ATP; ADP; phosphate; bind; released
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Since three positive charges are pumped out for every two allowed in, the cell is made more negative inside by the pump. We call this pump
electrogenic
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Na+/K+ ATPase (Na+/K+ pump)
Na+ gradient: high outside cell, low inside.
K+ gradient: low outside cell, high inside.
Pump wants to move both against their gradients.
ATP is used as energy source.
3 Na+ bind to pocket in pump protein
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Na+/K+ ATPase
Step 2:
3 Na+ expelled from cell.
ATP split to ADP + P + energy
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Na+/K+ ATPase
Step 3:
K+ pocket exposed
P released
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Na+/K+ ATPase
Step 4:
2 K+ enter cell.
Pump is reset to bind 3 more Na+
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What is an Antiport System?
It is a form of Active transport.When two ions move in opposite directions to drive the pump.
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What is a Symport System?
It is a form of Active transport.
A molecule and an ion move in the same direction to drive the pump.
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