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Biochem Phospholipids, Cholesterol, lipoproteins, steroid hormones
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What has the structure of a DAG with a phosphate on carbon 3?
Glycerophospholipids AKA phosphoglycerides
What are the four main functions of glycerophospholipids?
Cell membrane component
intracellular messengers
Anchors proteins to cell membranes
Lung surfactant (prevents alveoli from collapsing)
What are the two types of phosphoglycerides?
Plasmalogen
Plate-activating factor
What is the backbone of sphingolipids aka sphingomyelin?
Sphingosine (amino acid)
What originates from unsaturated fatty acids with 20 caarbons?
Eicosanoids
How do eicosanoids differ from hormones?
1. they are made in small amounts in all tissues
2. act locally, not transported like hormones
3. Not stored
4. G-protein mechanism
Leukotrines = ?
inflammation
What enzyme is present in most tissues and contributes to the health of gastric tissues?
COX-1
What enzyme is present in fewer tissues and are part of the immune/inflamatory response?
COX-2
What acts as the structural component of all membranes and is the precursor to bile acids, steroid hormones, and vitamin D?
Cholesterol
What is the regulatory enzyme in cholesterol synthesis?
HMG CoA reductase
Where does cholesterol synthesis occur?
Cytoplasm
What is needed for cholesterol synthesis?
NADPH
Acetyl CoA and ATP
What does A Happy Man Is Singing Carols stand for?
Acetyl CoA
HMG CoA
Mevalonate
Isoprene
Squalene
Cholesterol
What is a spherical macromolecular complexes of lipid and protein?
Lipoproteins
What is the main function of Lipoproteins?
Keep lipids soluble and transport them to plasma
What are TAGs transported from intestine to other tissues?
chylomicrons
Tags transported to fat tissue
VLDL
Cholesterol transported to peripheral tissues?
LDL
Cholesterol to liver
HDL
what do steroid hormones always start with?
Cholesterol
What are the first three steps in steroid synthesis?
Cholesterol => pregnenolone => Progesterone
What is the parent compound of all steroid hormones?
Pregnenolone or progesterone
Author
bradley.knox
ID
188199
Card Set
Biochem Phospholipids, Cholesterol, lipoproteins, steroid hormones
Description
biochem
Updated
2012-12-09T21:38:04Z
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