Mechanism for rapid transport of nutrients, waste products, respiratory gases and cells within the body
Specialized fluid connective tissue
Functions of Blood
- Transporting dissolved gases, nutrients , hormones & metabolic waste
- Regulate Ph and electrolyte composition of the interstitial fluids
- Restricting fluid loss through damaged vessels
- Defending against pathogens and toxins
- Regulating body temp by absorbing and redistributing heat
Blood is made up of?
- Red Blood Cells (RBCs)
- White Blood Cells (WBCs)
The three classes of plasma proteins are
Attack foreign proteins and pathogens
Most abundant proteins and major contributers to the osmotic pressure of plasma
antibodies and transport proteins
Bind small ions, hormones or compounds that might otherwise be lost at the kidneys or that have very low solubility in water
What is Fibrinogen
Plasma protein that that functions in blood clotting
Process by which all formed elements (RBCs, WBCs and platelets) are produced
Stem cells that divide to produce RBCs, WBCs and platelets (formed elements)
Red Blood Cells abbreviation and other name
Percentage of whole blood volume occupied by cellular elements
What do RBCs do?
- Transport CO2 and O2 within the blood stream
- Lack many organelles and usually degenerate aft 120 days in the blood stream
- Found in RBCs
- Globular protein formed from 4 subunits
- Each subunit contains a single molecule of heme & can reversably bind an O2 molucule
The formation of Red Blood Cells is called and occurs where?
Erthropoiesis takes place in the red bone marrow (myeloid tissue)
Erythropoietin (EPO) is?
- Erythropoiesis stimulating hormone
- Hormone is excreted when peripheral tissues are exposed to low O2 concentrations
Stages in RBC development include
- Substances that your immune defenses recognize as "normal"
- In other words you immune system ignores them rather than attacking them as foreign
What determines blood type?
Three surface antigens R, B & Rh
Four Blood Types & their antigens
- Type A: Blood has antigen A only
- Type B: Blood has antigen B only
- Type AB: Blood has both A & B antigens
- Type O: Blood has neither A nor B antigens
Contractility of the heart
Rate of heart beat
Conductivity of the heart