BIO CH 14

a picture of chromosomes aranged in pairs from largest to smallest

46 individual, or 23 pairs; 23 from egg and 23 from sperm

23

1

chart showing the relationship of traits within a family; square-male circle-female

human complete set of genetic information, 20,000-25,000

rhesus monkey

PKU phenylketunuria, albinism

huntingtons, dwarfism

sickle cell anemia

when you produce sickle shaped blood cells and they get stuck in the blood vessles and cause lots of apain and block the flow of blood damaging tissues/organs

when one x is randomly switched off and forms a Barr Body (the chromosome forms a dense region in the nucleus)

chromosome inactivation

when homologous chromosomes fail to separate

nondisjunction

if two copies of an autosomal chromosome fails to separate during meiosis

missing  a chromosome in a pair

entire sets of chromosome

roughly 6 billion

June 2000

an absent or faulty gene replaced by a normal working  gene

• an absent or faulty gene replaced by a normal working  gene
• the body can then make the correct protein or enzyme, eliminating the cause of the disorder
• viruses are then used because of their ability to enter a cells DNA
• virus particles are modified so they cannot cause disease
• a DNA fragment containing a replacement gene is spliced to viral DNA
• the patient is then infected with the modified virus particles which should carry the gene into cells to correct genetic defects