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Hormone-producing glands located superior to the kidneys; each consists of medulla & cortex areas.
Adrenal glands (suprarenals)
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Anterior pituitary hormone that influences the activity of the adrenal cortex.
Adrenocorticotropic hormone (ACTH)
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Initial reaction to stress.
Alarm reaction
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Hormone produced by the adrenal cortex that regulates Na+ reabsorption & K+ secretion by the kidneys.
Aldosterone
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An enzyme that catalyzes the formation of cyclic AMP from ATP.
Adenylate cyclase
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Potent vasoconstrictor activated by renin; also triggers release of aldosterone.
Angiotensin II
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Hormone that stimulates kidneys to reabsorb more water, reducing urine volume; produced by the hypothalamus & released by posterior pituitary
Antidiuretic hormone (ADH)
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Hormone released by certain cells of the heart atria that reduces blood pressure & volume by inhibiting nearly all events that promote vasoconstriction and Na+ & H20 retention.
Atrial natriuretic peptide (ANP)
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Hormone that lowers blood calcium levels only when present at high levels; released by thyroid.
Calcitonin
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A physiologically active metabolic derivative of cholecalciferol that is synthesized in the liver & kidney, stimulates the intestinal absorption of calcium.
Calcitriol
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Intracellular molecule generated by the binding of a chemical (hormone or neurotransmitter) to a plasma membrane receptor; mediates intracellular responses to the chemical messenger.
cAMP (second messenger)
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Intestinal hormone that stimulates gallbladder constraction & pancreatic juice release.
Cholecystokinin (CCK)
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Reduction in a cellular resonse to a molecule due to a decrease in the number of receptors on the cell surface.
Down regulation
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Homeostasis mechanism that monitors hormones within the body and self-corrects to maintain a therapeutic level of the hormone.
Endocrine feedback loop
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Chief hormone produced by the adrenal medulla, also called adrenaline.
Epinepherine
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Hormones that stimulates female secondary sex characteristics; femal sex hormone.
Estrogens
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Hormone that stimulates ovarian follicle production in females & sperm production in males; produced by anterior pituitary.
Follicle-stimulating hormone (FSH)
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Hormone that regulates gastric juice secretion by stimulating HCL production; secreted in stomach.
Gastrin
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Sequence of physiological reaction to prolonged stress that includes alarm, resistance & exhaustion.
General adaptation syndrome
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Hormone that targets anterior pituitary to release growth hormones; synthesized in hypothalamus.
Growth hormone-releasing hormone (GHRH)
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Hormone that raises glucose level of blood; formed by alpha cells of pancreatic islets.
Glucagon
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Formation of glucose from non-carbohydrate molecules.
Gluconeogenesis
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Breakdown of glycogen to glucose.
Glycogenolysis
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Regulatory molecules inside cells that couple membrane receptors to intracellular second messengers.
G-proteins
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Hollow muscle that pumps blood throughout the blood vessels by repeated, rhythmic contractions. Found in all animals with a circulatory system.
Heart
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Hormone that stimulates growth in general; produced by anterior pituitary.
Human growth hormone (hGH)
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Hormone specifically bound to it's receptor either on the plasma membrane or intracellularly.
Hormone-receptor complex
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Steroidal or amino acid-based molecules released to the blood that act as chemical messengers to regulate specific body functions.
Hormones
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Region of the diencephalon forming the floor of the 3rd ventrical of the brain; directly above the pituitary gland.
Hypothalamus
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Glycoprotein hormone that inhibits secretion of follicle stimulating hormone; secreted by pituitary gland.
Inhibin
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Hormone that enhances the carrier-mediated diffusion of glucose in tissue cells, lowering blood glucose levels.
Insulin
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Pair of vertebrate organs situated in the body cavity near the spinal cord that excretes wast products of metablism.
Kidneys
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An enzyme that modifies other proteins by chemically adding a phosphate group, usually results in a functional change of the protein by changing enzyme activity, cellular location, or association with other proteins.
Kinase proteins
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Type of hormones that encompass all amino acid-based hormones except thyroid hormones; act on receptors in the plasma membrane.
Lipid insoluble hormones (water soluble)
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Type of horome (steroid & thyroid) that act on intracellular receptors which directly activate genes.
Lipid soluble hormones
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Lobed accessory organ that overlines the stomach; produces bile to help digest fat and serves metabolic & regulatory functions.
Liver
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Biologically active lipids released by nearly all cell membranes. Typically highly localized, acting as paracrines & autocrines, so do not fit the definition of true hormones.
Eicosanoids
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Hormones that act within tissues that produced them to stimulate actions required for growth:
1. Uptake of nutrients from blood & their incorporation into proteins & DNA allowing growth by cell division;
2. Formation of collagen & deposition of bone matrix.
Insulin-like growth factors (IGF)
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Local hormone that is a gaseous chemical messenger; diverse functions include participation in memory formation in the brain, and causing vasodilation throughout the body.
Nitric oxide
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Anterior pituitary hormone that aids maturation of cells in the ovary & triggers ovulation in females. In males, causes interstitial cells of the testes to produce testosterone.
Luteinizing hormone (LH)
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CNS neurotransmitter involved in control of appetite; low levels found in plasma. Comes from pro-opiomelancortin (POMC).
Melanocyte-stimulating hormone (MSH)
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Hormone secreted by the pineal glands; secretion peaks at night & helps set sleep-wake cycles; also a powerful anti-oxidant.
Melatonin
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Catecholamine neurotransmitter & adrenal medullary hormone, asociated with sympathetic nervous system activation.
Norepinephrine
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Female reproductive organs in which ova are produced; female gonad.
Ovaries
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Hormone synthesized in the hypothalamus & secreted by the posterior pituitary; stimulates contraction of uterus during childbirth & ejection of milk during nursing.
Oxytocin
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Gland located behind the stomach, between the spleen & duodenum; produces both endocrine & exocrine secretions.
Pancreas.
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Small endocrine glands, usually 4, located on the posterior aspect of the thyroid gland.
Parathyroid glands
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Hormone released by the parathyroid glands that regulates blood calcium level.
Parathyroid hormone (PTH) phosphorylated enzymes
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Hormone-secreting part of the diencephalon of the brain thought to be involved in setting the biological clock & influencing reproductive function.
Pineal gland
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Neuroendocrine gland located beneath the brain that serves a variety of functions including regulation of gonads, thyroid, adrenal cortex, lactation & water balance.
Pituitary gland
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Glandular part of pituitary gland that produces hormones in response to signals from hypothalamus.
Anterior lobe (adenohypohysis)
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Stalk of tissue that connects the pituitary gland to the hypothalamus.
Infundibulum
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Portion of the pituitary derived from the brain that stores hormones produced in the hypothalamus.
Posterior lobe (neurohypophysis)
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Hormone partly responsible for preparing the uterus for the fertilized ovum.
Progesterone
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Adenohypophyseal hormone that stimulates the breasts to produce milk.
Prolactin (PRL)
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Protein that binds specifically with chemical molecules.
Receptor
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Hormone produced by placenta that causes pelvic ligaments & pubic symphysis to relax, widen & become more flexible in preparation for childbirth.
Relaxin
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Hormones secreted by neurons in the ventral hypothalamus that circulate to the anterior pituitary where they regulate secretion of its hormones.
Releasing & inhibiting hormones
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Hormone released by the kidneys that is involved with raising blood pressure.
Renin
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External sac enclosing the testes.
Scrotum
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Peptide secreted from the duodenum, triggering pancreas & liver to to release bicarbone-rich juice and inhibits secretory activity of the stomach.
Secretin
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Temporary reservoir in the GI tract where chemical breakdown of proteins begins & food is converted into chyme.
Stomach
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The specific tissues that specific hormones are meant to influence.
Target cells
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Male primary reproductive organ that produces sperm; male gonad.
Testes
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Male sex hormone produced by the testes; during puberty promotes virilization and is necessary for normal sperm production.
Testosterone
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Lympoid organ & endocrine gland active in immune response; site of maturation of T lymphocytes.
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One of the larges of the body's endocrine glands; straddles the anterior trachea.
Thyroid
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Tissue mass that connect the two lateral lobes of the thyroid.
Isthmus
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Major hormones secreted by the thyroid follicles, stimulates enzymes concerned with glucose oxidation; Thyroxine (T4) Iodine containing hormone secreted by the thyroid gland; accelarates cellular metabolic rate in most body tissues.
Thyroid hormones (T3 & T4)
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Hypothalamic peptide that triggers TSH release from cells of the anterior pituitary.
Thyrotropin-releasing hormone (TRH; prolactin releasing hormone)
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Adenohypophyseal hormone that regulates secretion of thyroid hormones.
Thyroid stimulating hormone (TSH)
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A process by which target cells form more receptors in response to rising blood levels of the specific hormones to which they respond.
Up regulation
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