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NCTI- Pharmacology- Drug List C- Mannitol
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Mannitol
trade name
Osmitrol
Mannitol
class
osmotic diuretic
Mannitol
mechanism of action
Inhibits sodium and water absorption in the kidneys
Promotes fluid movement from the intracellular into the extracellular space
Dehydrates brain tissue to decrease ICP
Mannitol
indications
Acute cerebral edema
Blood transfusion reactions
Mannitol
contraindications
Acute pulmonary edema
Severe pulmonary congestion
Hypovolemia
Mannitol
side effects
Cardiovascular
: chest pain
Neurological
: mental status change
Mannitol
precautions
May cause transient increase in intravascular volume
May cause CHF
May cause sodium depletion (hyponatremia)
Will crystallize in low temperatures
Should be used with in-line filters
Mannitol
interactions
Should not be administered during blood transfusions
Mannitol
routes
IV, IO, IVPB
Mannitol
onset and duration
Onset in 15 minutes to reduce ICP, 1-3 hours for diuresis; may last 3-8 hours
Mannitol
dosages
Adult
: 1.5 – 2 gm/kg slow IVPB/IV
Pediatric
: 0.25 – 0.5 gm/kg over 60 minutes
Mannitol
notes
none
Author
RunNickMarini
ID
18556
Card Set
NCTI- Pharmacology- Drug List C- Mannitol
Description
NCTI- Pharmacology- Drug List C- Mannitol
Updated
2010-05-10T03:23:27Z
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