NCTI- Pharmacology- Drug List C- Mannitol

Mannitol
trade name

Osmitrol
Mannitol
class

osmotic diuretic
Mannitol
mechanism of action
- Inhibits sodium and water absorption in the kidneys
- Promotes fluid movement from the intracellular into the extracellular space
- Dehydrates brain tissue to decrease ICP
Mannitol
indications
- Acute cerebral edema
- Blood transfusion reactions
Mannitol
contraindications
- Acute pulmonary edema
- Severe pulmonary congestion
- Hypovolemia
Mannitol
side effects
- Cardiovascular: chest pain
- Neurological: mental status change
Mannitol
precautions
- May cause transient increase in intravascular volume
- May cause CHF
- May cause sodium depletion (hyponatremia)
- Will crystallize in low temperatures
- Should be used with in-line filters
Mannitol
interactions

Should not be administered during blood transfusions
Mannitol
routes

IV, IO, IVPB
Mannitol
onset and duration

Onset in 15 minutes to reduce ICP, 1-3 hours for diuresis; may last 3-8 hours
Mannitol
dosages
- Adult: 1.5 – 2 gm/kg slow IVPB/IV
- Pediatric: 0.25 – 0.5 gm/kg over 60 minutes
Mannitol
notes

none

Author

RunNickMarini

18556

Card Set

NCTI- Pharmacology- Drug List C- Mannitol

Description

NCTI- Pharmacology- Drug List C- Mannitol

Updated

2010-05-10T03:23:27Z

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