ARBs - Angiotensin II Blockers

Prevents the release of aldosterone ("sodium saver")

Acts on the RAAS - renin angiotensin aldosterone system

• Blocks angiotensin II from the AT1 receptorsfound in many tissues
•    -  blocks the vasoconstrictor effects of angiotensin II at the receptor site

Causes vasodilation and decreased peripheral resistance

dizziness, hypotension

lifethreatening: angioedema

potent vasoldilator

• Peaks - 6 hours
• duration - 24 hours

valsartan - Diovan

Not taken during pregnancy