Pulmonary

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Rapid acting beta2-agonist
- Names
- MOA
- Use
- Names: albuterol; pirbuterol; bitolterol
- MOA: bronchodilators that relax airway smooth muscle; rapid onset of action
- Use: first line of therapy in mild intermittent cases; during exacerbations
Long-acting beta2-agonist
- Names
- MOA
- Use
- Names: salmeterol; formoterol; sustained-release albuterol
- MOA: Bronchodilators that relax airway smooth muscle; gradual onset; sustained activity
- Use: regular use for moderate persistent or severe asthma
Inhaled corticosteroids
- Names
- MOA
- Uses
- Names: beclomethasone; flunisolide
- MOA: decrease number and activity of cells involved in airway inflammation
- Uses: mild persistent or worse cases; frequently combined with beta2 agonist use
Leukotriene inhibitors
- Names
- MOA
- Uses
- Names: zafirlukast; zileuton
- MOA: block activity or production of leukotrienes that are involved in inflammation and bronchospasm
- Uses: oral agents; adjunctive therapy in mild persistent or worse cases
Mast cell stabilizing agents
- Names
- MOA
- Uses
- Names: cromolyn; nedocromil
- MOA: stabilizes mast cells; anti-inflammatory prophylaxis
- Uses: NOT useful acutely; anti-inflammatory prophylaxis in mild persistent cases
Theophylline
- MOA
- Uses
- MOA: bronchodilator
- Uses: useful as adjunct in mild persistent or worse cases (no longer 1st line of therapy)
Anticholinergic agents
- Names
- MOA
- Uses
- Names: ipratropum
- MOA: blocks vagal-mediated smooth muscle contraction
- Uses: adjunctive therapy in moderate to severe cases
Systemic steroids
- Names
- MOA
- Uses
- Names: methylprednisolone; prednisone
- MOA: decrease number and activity of of cells involved in ariwary inflammation
- Uses: adjunctive therapy in severe refractory cases

Author

sini

184880

Card Set

Pulmonary

Description

Asthma Medications

Updated

2012-11-22T03:53:05Z

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