-
the study of the circulatory system, including the blood, lymph, heart, arteries, veins, and lymph vessels
Angiology
-
the study of blood
Hematology
-
- transport of O2, CO2, food, wastes, hormones, etc.
- temperature regulation.
- control of pH (the hydrogen ion, H+, concentration).
- control of water balance.
- defense of against infection (phagocytosis) and immunity.
- repair & regeneration processes (healing process).
Functions of the blood
-
- Color is red
- Temperature is 38° C or 100.3° F
- Specific Gravity is 1.041 to 1.067 (Water's is 1.000)
- Viscosity (Resistance to flow) is 4½ to 5½ times that of water
- pH (hydrogen ion concentration) is 7.3 to 7.4 (slightly basic or alkaline)
- Blood volume is 5 to 6 quarts or (1/20 to 1/13 of total body weight) for average adult.
Characteristics of the blood
-
- Blood Cells = Corpuscles = Formed Elements
- Red Blood Cells, RBC's, Erythrocytes
- White Blood Cells, WBC's, Leukocytes
- Platelets, Thrombocytes
Parts of Blood
45 %
-
Plasma (liquid portion of the blood with dissolved components)
Parts of Blood
55 %
-
Biconcave shape (more or less round and flat with an indention on each side)
7.7 microns in diameter
4,000,000 to 6,000,000 per mm3 (cubic millimeter)
Erythrocytes
Characteristics of Red Blood Cells
-
Function is to Carry O2 and CO2 (Oxygen and Carbon dioxide)
Erythrocytes
-
Contain Hemoglobin (Protein containing Iron = Fe)
Erythrocytes
-
Hemoglobin breaks down as the RBC's decompose forming Biliverdin (green pigment) then Bilirubin (yellow pigment) forms.
Erythrocytes
-
Liver is responsible for removing these bile pigments from the circulatory system.
If it does not then Jaundice (Icterus) occurs.
-
Usually stored in the gall bladder (bile sac).
bile
-
-
-
Passing through the vessel wall
Diapedesis
Characteristics of Red & White Blood Cells & Thrombocytes (Platelets)
-
Life span is probably between 1 month and 4 months
Erythrocytes
-
(Actually several different types but described as one)
Spherical shape (like a ball)
Vary in size, but average is about 10 microns
5,000 to 10,000 per mm3
Leukocytes
Characteristics of White Blood Cells
-
Function is to fight infections
Leukocytes via Phagocytosis
-
surround, engulf and destroy foreign substances in the blood
Phagocytosis
-
white blood cells are sometimes called
Phagocytes
-
Life span may vary from a few days to a few weeks
Leukocytes
-
Disc shape (sometimes referred to as fragments)
Vary in size, but about 3 microns in diameter
130,000 to 360,000 per mm3
Thrombocytes
Characteristics of Platelets
-
Function is the Clotting or Coagulation of blood
Thrombocytes
Characteristics of Platelets
-
92 % to 95 % of Plasma
Water
Components of Plasma
-
5 % to 8 % of Plasma
Dissolved Components
Components of Plasma
-
Blood Proteins
Serum albumin
Serum globulin
fibrinogen
Inorganic Salts of Na, K, Ca, & Mg
Chlorides
Bicarbonates
Phosphates
Sulfates
Nutrients
Carbohydrates (Glucose)
Fats
Proteins
Minerals
Vitamins
Wastes
Respiratory Gases
02
CO2
N2
Enzymes
Hormones
Antibodies
Others
Drugs
Anything else
Dissolved Components
Components of Plasma
-
Plasma that has the clotting factors removed.
Serum
-
40 - 43 % Population UNIVERSAL DONOR
Blood Type O
-
40 - 45 % Population
Blood Type A
-
10 - 15 % Population
Blood Type B
-
4 - 5 % Population UNIVERSAL RECIPIENT
Blood Type AB
-
UNIVERSAL DONOR
Type O Blood
-
UNIVERSAL RECEPIENT
Type AB blood
-
Discovered in the rhesus monkey
Rh factor
-
-
85 % Population
Rh + (positive) – means you have it
-
15 % Population
Rh - (negative) – means you do NOT have it
-
Condition in which the pregnant mother is Rh negative and the Baby is Rh positive.
Erythroblastosis fetalis
-
Mother's body builds up antibodies against the Rh factor from Baby's body which in essence will cause the Mother's body to reject the Baby's body (from within by its own blood).
Erythroblastosis fetalis
-
It does not usually occur until after the first pregnancy where the above conditions exists.
Erythroblastosis fetalis
-
Treatments may involve either Rho Gamma treatments given to Rh negative pregnant women who may be carrying an Rh positive Baby or transfusion of the Baby while in utero.
Erythroblastosis fetalis
-
(1) Thromboplastin(thrombokinase) (cephalin)
(2) Prothrombin
(3) Calcium
(4) Fibrinogen
(5) Vitamin K
Substances in blood that are involved in clotting
-
(1) Antithrombin
(2) Heparin (Antiprothrombin)
Substances in blood that inhibit clotting
-
(1) Prior to clotting – prothrombin is inactive as the result of presence of antiprothrombin
(2) Fragmentation of blood platelets releases thromboplastin
(3) Thromboplastin neutralizes antiprothrombin, thus liberating prothrombin
(4) Prothrombin + Ca forms thrombin
(5) Thrombin + fibrinogen forms fibrin
(6) Fibrin + blood cells forms the clot
Chemistry of clotting blood
-
3 to 5 minutes
Coagulation time
-
1. "Wall" dividing the thoracic from the abdominal cavities.
Diaphragm
-
2. Action of blood cells escaping the vascular system by passing through the walls of the capillaries is called:
Diapedesis
-
3. Arteries have three layers in their walls while arterioles have _____.
two layers
-
4. Blood cells make up approximately _____% of the blood volume.
45 %
-
5. Blood cells responsible for clotting are called _____.
Thrombocytes
-
6. Blood cells responsible for fighting‑off infections.
-
7. Blood cells which contain hemoglobin.
-
8. Blood type _____ is said to be the universal donor.
O
-
9. Blood vessels that carry the blood in the general direction towards the heart.
Veins
-
10. Innermost layer of an artery or vein is made up of this type of basic (elemental) body tissue.
Endothelium
-
11. Middle layer of the wall of the heart is called _____.
Myocardium
-
12. Name of the individual credited with the discovery of the circulation of blood.
-
13. Name six (6) Functions of the blood.
- - transport of O2, CO2, food, wastes, hormones, etc.
- - temperature regulation.
- - control of pH (the hydrogen ion, H+, concentration).
- - control of water balance.
- - defense of against infection (phagocytosis) and immunity.
- - repair & regeneration processes (healing process).
-
14. Normal pH of blood is _____(a number).
7.3 to 7.4
-
15. Outer layer of an artery or vein is called the tunica _____.
externa
-
16. Portion of the blood that is about 95% water.
Plasma
-
17. Position with the body standing erect, facing the observer, and the hands at the side with the palms facing the observer is said to be the _____.
anatomical study
-
18. Process by which a blood cell surrounds, engulfs and destroys foreign substances:
Phagocytosis
-
19. Process by which leukocytes surround, ingest, and destroy foreign substances in the blood stream.
Phagocytosis
-
20. Region immediately inferior to the hypochondriac region of the abdomen.
LUMBAR REGION
-
21. Study of blood is called _____.
Hematology
-
22. Study of the circulatory system, including the blood, lymph, heart, arteries, veins, and lymph vessels is called _____.
Angiology
-
23. System of the body that deals with the blood, heart, arteries, veins, and lymphatics is called _____.
circulatory system
-
24. Term visceral refers to _____.
pertaining to the viscera, or the internal organs contained within a cavity.
-
25. Term which means, the study of blood.
Hematology
-
26. Vessel leaving the heart that carries blood towards all parts of the body.
Artery
-
27. Characteristics of the blood -
- Color is due to what substance in the blood.
- Temperature is _____.
- Specific Gravity is slightly greater than _____.
- pH (hydrogen ion concentration) is _______ (This is slightly _______.)
- - ?
- - 38° C or 100.3° F
- - 1.041 to 1.067
- - 7.3 to 7.4, basic or alkaline
-
28. Another name for Blood Cells is ______ or ______ __________.
Corpuscles, Formed Elements
-
29. The three (3) types of blood cells:
1. _____________ and alternate name ______________
2. _____________ and alternate name ______________
3. _____________ and alternate name ______________
- 1. Erythrocytes, Red Blood Cells
- 2. Leukocytes, White Blood Cells
- 3. Thrombocytes, Platelets
-
30. Blood cells make up ______ % of blood volume.
45 %
-
31. Plasma makes up ______ % of blood volume.
55 %
-
32. Characteristics of Red Blood Cells
Shape
Size
Number
Function
Contains
Life span
Diapedesis
- Biconcave shape (more or less round and flat with an indention on each side)
- 7.7 microns in diameter
- 4,000,000 to 6,000,000 per mm3 (cubic millimeter)
- Function is to Carry O2 and CO2
- Hemoglobin
- Life span is probably between 1 month and 4 months
- Passing through the vessel wall
-
33. Characteristics of White Blood Cells
Shape
Size
Number
Function
Life span
Diapedesis
- Spherical shape (like a ball)
- Vary in size, but average is about 10 microns
- 5,000 to 10,000 per mm3
- Function is to fight infections
- Life span may vary from a few days to a few weeks
- Passing through the vessel wall
-
34. Characteristics of Platelets
Shape
Size
Number
Function
Diapedesis
- Disc - sometimes referred to as fragments
- Vary in size, but about 3 microns in diameter
- 130,000 to 360,000 per mm3
- Clotting or Coagulation of blood
- Passing through the vessel wall
-
35. Another name for Gall Bladder is _______.
bile sac
-
36. Define Bilirubin
Hemoglobin breaks down as the RBC's decompose forming Biliverdin (green pigment) then Bilirubin (yellow pigment) forms.
-
37. Define Biliverdin
Hemoglobin breaks down as the RBC's decompose
green pigment
-
38. Define Icterus
Jaundice
-
39. Define Jaundice
Icterus
-
40. Define Phagocytes
white blood cells that surround, engulf and destroy foreign substances in the blood
-
41. Define Phagocytosis
surround, engulf and destroy foreign substances in the blood
-
42. Define Serum
Plasma that has the clotting factors removed
-
43. List some of the common Components of Plasma:
Water (92 % to 95 % of Plasma is Water)
- Dissolved Components (5 % to 8 % of Plasma are the following
- Blood Proteins
- Serum albumin
- Serum globulin
- fibrinogen
- Inorganic Salts of Na, K, Ca, & Mg
- Chlorides
- Bicarbonates
- Phosphates
- Sulfates
- Nutrients
- Carbohydrates (Glucose)
- Fats
- Proteins
- Minerals
- Vitamins
Wastes
- Respiratory Gases
- O2
- CO2
- N2
Enzymes
Hormones
Antibodies
- Others
- Drugs
- Anything else
-
44. The UNIVERSAL DONOR is Type ______ Blood.
Type O
-
45. The UNIVERSAL RECEPIENT is Type ______ blood.
Type AB
-
46. What are the four (4) Blood Types?
- Type O
- Type A
- Type B
- Type AB
-
47. What is Erythroblastosis fetalis?
Condition in which the pregnant mother is Rh negative and the Baby is Rh positive.
-
48. What is the Rh factor ?
blood protein
-
49. What percentage of the population does not have the Rh factor?
15 % Population
-
50. What percentage of the population has the Rh factor?
85 % Population
-
51. Who can give blood to another person?
Type O
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