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Chest pain that does not change with body position or respiration
CAD
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Plueritic pain ddx
PE, Pneumo, Pleuritis, Pericarditis, Pneumothorax
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Positional Pain ddx
Pericarditis
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S3 Gallop suggests
dilated left ventricle
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S4 Gallop suggests
left ventricle hypertrophy
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best test for ischemic chest pain
EKG
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Time frame that CK-MB and Troponin
rises3-6 hrs after start of CP
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Main diff btw CK-MB and TroponinCK-MB
only stays elevated 1-2 days while troponin stays elevated 1-2 wks
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Time frame that Myoglobin rises
1-4 hrs after start of CP
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When do you do a stress test
when CP isnt acute and intial EKG & cardiac enzymes don't establish dx
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When do I answer dipyridamole or adenosine thallium stress test or dobutamine echo
pt who cannot exercise to target HR of >85% of max: COPD, Amputation, Deconditioning, weakness/prev stroke, lower-extremity ulcer, dementia, obesity
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When do I answer exercise thallium testing or stress echo
EKG is unreadable for ischemia: LBBB, digoxin use, pacemaker in place, Left ventricular hypertrophy, any baseline abnorm of ST segment of the EKG
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What do you use to stress test in obese and large breasted pts
Sestamibi nuclear stress test
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Best initial tx for Acute coronary syndrome
aspirin
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% mortality reduced when using aspirin for MI and in unstable angina
25% MI and 50% UA
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Other tx giving in ACS but does not lower mortality
O2, nitrates, morphine
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Tx that will lower mortality in STEMI
thrombolytics and primary angioplasty (both dependent on time)
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PCI must be performed c/in what time frame
90mins of arrival at the ED for STEMI
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Angioplasty or med tx (aspirin, BB, statins) is better at decreasing mortality in stable angina
medical tx (aspirin, BB, statins)
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If PCI cannot be performed c/in the set time frame then what should be done
thrombolytics
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when are thrombolytics indicated
CP for <12 hrs and has ST elevation in 2 or more leads; new LBBB
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what is the time frame for thrombolytics
given c/in 30mins of pts arrival to ED c/pain
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what has the single greatest efficacy in lowering mortality in STEMI
PCI
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What should be given to ACS pts in addition to O2, aspirin, angioplasty or thrombolytics
BB & ARB or ACEI
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What drug is given to pts c ACS, lowers mortality but isn't time dependent
BB
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ACEI and ARBs lower mortality in which ACS pts
pts c left vent dysfunction or systolic dysfunction
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What med should always be given to all pts c ACS
statin medications (atorvostatin)
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ACS tx that always lower mortality
aspirin, thrombolytics, angioplasty, metoprolol, statins (atorvostatin), clopidogrel
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ACS tx that lowers mortality in certain conditions
ACEI (if EF is low); ARBs (if EF is low)
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CS tx that do not lower mortality
O2, morphine, nitrates, CCB, Lidocaine, Amiodarone
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When is clopidogrel the answer in ACS
when pt has ACS and is allergic to aspirin or pt is undergoing angioplasty
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When is CCB the answer in ACS
when pt has intolerance to BB (eg asthma), cocaine induced CP, coronary vasospasm (prinzmetal angina)
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When is pacemaker the answer in ACS
3rd degree block, Mobitz type II, Bifasicular block, new LBBB, symptomatic bradyc
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When is lidocaine or amiodarone the answer in ACS
ONLY in vent fib or vent tachyc (DO NOT give to prevent vent arrythmias
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all complications of MI can lead to
hypotension
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Complication of MI: Cardiogenic shock dx tx
dx: echo, swan ganz tx: ACEI, urgent revasc
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Complication of MI: Valve rupture dx tx
dx: echo tx: ACEI, nitroprusside, intra-aortic balloon pump as bridge to sx
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Complication of MI: Septal rupture dx tx
Complication of MI: Septal rupture dx txdx: echo, rt heart catheter showing a step up in sat from rt atr to rt vent tx: ACEI, nitroprusside, urgent sx
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Complication of MI: Myocardial wall rupture dx tx
dx: echo; tx: pericardiocentesis, urgent cardio repair
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Complication of MI: Sinus bradyc dx tx
dx: EKG; tx: Atropine followed by pacemaker if there are still symptoms
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Complication of MI: 3rd degree block dx tx
dx: EKG, canon "a" waves; tx: atropine and pacemaker
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Complication of MI: Rt vent infarction dx tx
dx: Rt ventricular leads on EKG; tx: fluid loading
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All pts post MI should go home on what meds
aspirin, BB, statin, ACEI
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Predominant diff in mgmt of NSTEMI vs STEMINSTEMI: no thrombolyic use, heaparin used routinely, glycoprotein IIb/III inhib lower mort (esp in pts undergoing angioplasty)
NSTEMI: no thrombolyic use, heaparin used routinely, glycoprotein IIb/III inhib lower mort (esp in pts undergoing angioplasty)
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Both ARBs and ACEI have what SE
hyperkalemia
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Meds used routinely in SA mgmt
aspirin, metoprolol
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Med used in anginal pain but do not reduce mortality
nitrates
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When should ARBs and ACEI be used in SA mgmt
in pts c CHF, Systolic dysfunction, low EF
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Why is an angiography done?
to determine who is a candidate for CABG
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What are the indications for CABG
3 coronary vessels c > 70% stenosis, left main coronary art stenosis >70%
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When is a statin recommended
in ACS pt c LDL > 130
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Goal of statin tx
in CAD pt LDL <100; in diabetic pt c CAD LDL <70
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