Diphenhydramine blocks histamine release, thereby reducing bronchoconstriction, vasodialation and edema. It suppresses central cholinergic activity and prolongs the action of dopamine by inhibiting its reuptake and storage.
Indications
Anaphlylaxis, allergic reactions and dystonic reactions
Contraindications
Asthma and other lower respiratory diseases
Precautions and Side Effects
- Drowsiness
- Tachycardia
- Dizziness
- Hypertension / Hypotension
Dosage ( Adult)
25 to 50mg IV/IM
Dosage (Pedi)
6 - 12 year olds- 12.5 to 25mg IV/IM
under 6 years old- 2 to 5mg/kg IV/IM, not to exceed 25mg