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REVIEW 8
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What is FGF responsible for
Angiogenesis
Embryonic development
Hematopoiesis
wound repair (recruitment)
Streptomycin MOA
Binds 30S ribosomal subunit and inhibits initiation complex
Alcohol and gallstones can lead to what
acute pancreatitis
What are the subcutaneous neurofibromas of NF1
They are schwann cells which are derived from neural crest cells
Burkitts lymphoma gene
8:14 translocation -> c-myc - transcription activation
Global ischemia of the brain affects what first
Pyramidal cells of hippocampus
then pyramidal cells of neocortex
purkinje cells of cerebellum
Classical galactosemia = what type of inheritance
Autosomal recesive
Wiskott Aldrich Syndrome treatment
HLA matching bone marrow transplant
Why is there increased expiratory flow rate with restrictive lung disease
Increased elastic recoil and increased radial traction on the conducting airways
SIADH leads to
Euvolemic hyponatremia
P bodies
Regulate mRNA
Intrapartum antibiotic for Group B strep
Penicillin
Lung adenocarcinoma
Peripheral involvement
More common in women and nonsmokers
Solid retroperitneal structures
Pancreas
kidney
adrenal glands
Tryptase
Released from mast cells in anaphylaxis
What stimulates mast cell degranulation
IgE accumulation
AIDS most common brain lesion
primary cell lymphoma from B cells (EBV)
Otitis externa in diabetic
P. aeruginosa
nonlactose fermenting, oxidase + motile gram negative
HAV decontamination
Chlorination
bleach
formalin
UV irradiation
boiling
Cauda Equina syndrome
Low back pain that goes to legs
saddle anesthesia
loss of anocutaneous reflex
bowel/bladder dysfunction
no ankle jerk relfex
(S2-S4)
Foscarnet side effects
Renal wasting of magnesium
decreased PTH stimulation -> dec calcium
both contribute to seizures
Phenelzine
irreversible inhibitor of MAO A and B
High blood gas partition coefficient
Slower onset
higher potency
Thiopental quick action
redistribution to the fat and muscle
Cyprheptadine
5HT receptor antagonist
Inhaled anesthetic with high arteriovenous gradient
High solubility -> slow onset
Papillary necrosis
Caused by Ischemia
:
Sickle cell disease of trait
Diabetes
Acute pyelonephritis
analgesics (Phenacetin)
Dofetilide
Class 3 (K+ ) antiarrhythmic
Fenoldapam
Activates adenyly cyclase -> increased cAMP --> vasodilation -> dec systemic resistance
Good perfusion for the kidney
Neurofibromatosis
Cafe au-lait spots
multiple neurofibromas
lisch nodules
Prostacyclin
From endothelium
vasodilates
inhibits platelet aggregation
increase vascular permeability
Pineal germinomas
Precocious puberty (BhCG)
obstructive hydrocephalus
Parinaud syndrome
Patient presents with postpartum blues what to do
See them in 2 weeks because this is when postpartum depression can be diagnosed and treated
Fibrates and fertile on cholesterol gallstones
Estrogen increases HMG CoA reductase -> more cholesterol
Fibrates decrease 7a hydroxylase
both lead to cholesterol gallstones
Acute viral hepatitis histo
ballooning degeneration
hepatocyte necrosis
portal inflammation
Silicosis characteristics
Eggshell calcification of hilar nodes
birefringent silica particles surrounded by fibrous tissue
Haloperidol S/E
high potency anti-psychotic -> nigrostriatal pathway inhibition of dopamine -> affects skeletal muscle tone
Bronchoalveolar carcinoma Histo
Tall columnar cells that line alveolar septa without invasion
Cancers that release hypercoagulable products ->
Nonbacterial thrombotic endocarditis
Trousseau syndrome
A positive VDRL and pleocytosis is significant of what?
Neurpsyphillis with Gummaas
What bacteria can undergo transformation
S. pneumo
H. influenza
N, meningitidis
How would an infant with hydrocephalus present?
irritability
poor feeding
muscle tonicity
hyperreflexia
How is the work of breathing decreased in a patient with pulmonary fibrosis
They have increased elastic resistance so work of breathing is decreased by taking shallow rapid breaths
Burkitt Lymphoma (8:14) is
c-myc = transcription factor
Presentation of rabies encephalitis
reslessness, agitation and dysphagia which later on leads to coma
Bells palsy are expected to have what ear codition
hyperacusis because CN VII innervates the stapedius muscle
How does Crohns disease lead to kidney stones
Ca binds lipid in the intestine -> increase absorption of oxalate by the gut =-> stones in the kidney
What is the result of duodenal S cell
They secrete secretin ->
increase bicarbonate
decrease Cl-
Why should you not do a biopsy of hemangioma
Risk of fatal hemorrhage
low d potential
What are long duration benzos
chlordiazaepoxide
clorazepide
diazepam
Flurazepam
Blastomycosis causes what
Pulmonary disease in the immunocompetent
Disseminated mycosis in immunocompromised patients
How does TCA cause cardiac arrhythmia
The inhibit fast Na channels of cardiac myocytes -> cardiac arrhythmia
What is Pompes
Alpha glucosidase deficiency that leads to accumulation of glycogen into lysosomes
Amitryptiline side effect when used for diabetic neuropathy
blocks Ach receptor -> Hyperthermia, flushing, urinary retention
Vitamin B 6 and dopamine
V B6 is needed for decarboxylase reactions so leads to peripheral breakdown of L-dopa
Digoxin toxicity
Fatigue
Blurry vision
change in color perception
N/V/D abdominal pain
confusion
delirium
USED FOR ATRIAL FIB 2ND LINE
Atheroembolic Renal disease
cholesterol emboli obstructing renal arterioles
Author
lazzsant
ID
183331
Card Set
REVIEW 8
Description
REVIEW 8
Updated
2012-11-14T19:30:25Z
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