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Terbutaline
trade name
Brethine
-
Terbutaline
class
- Sympathomimetic Bronchodilator
- Tocolytic (in preterm labor)
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Terbutaline
mechanism of action
- 1. Relaxes bronchial smooth muscle causing bronchodilation
- 2. Relaxes uterine smooth muscle inhibiting contractions
-
Terbutaline
indications
- 1. Moderate to severe asthma
- 2. Bronchospasms associated with COPD
- 3. Secondary to Magnesium Sulfate in preterm labor to inhibit contractions
-
Terbutaline
contraindications
Uncontrolled tachydysrythmias
-
Terbutaline
side effects
- Cardiovascular: palpitations, tachycardia, dysrhythmias, hypertension, PVCs
- Respiratory: paradoxical bronchospasm
-
Terbutaline
precautions
Use with cautions in patients with cardiac disease
-
Terbutaline
interactions
- 1. Beta Blockers will decrease the actions
- 2. MAO inhibitors may cause hypertensive crisis
-
Terbutaline
routes
SQ, IV, IO, IVPB
-
Terbutaline
onset and duration
Onset is immediate and may last 15 minutes
-
Terbutaline
dosages
- Adult:
- Bronchodilation: 0.25 mg SQ. May repeat once in 15-30 minutes
- Tocolytic: 10 mcg/min IV/IVPB titrated to a max of 80 mcg/min
Pediatric: 0.01 mg/kg SQ. Maximum dosage is 0.25 mg.
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