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Substance abuse
- occurs at any age
- most common cause of disability and death worldwide
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Commonly abuse substances include
- alcohol
- cocaine
- amphetamine
- lysergic acid diethylamide (LSD)
- phencyclidine (PCP)
- prescription drugs
- benzodiazepines
- barbiturates
- opiates
- marijuana
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What is a substance of abuse?
- a pattern of harmful use of any substance for mood-altering purposes
- substances that can be abused for their mood-altering purposes that are not drugs: inhalants, solvents
- drugs that can be abused that have no mood-altering or intoxication properties: anabolic steroids
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What is addiction?
compulsive use and overwhelming involvement with a drug where an addict is spending an increasing amount of time obtaining, using and recovering from drug
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Physical dependence
- results in physical changes to the brain
- not a matter of willpower but actual physiological changes occurring
- physical effects occur when drug is stopped or its effects are counteracted by a specific antagonist
- drugs causing strong physical dependence include: opiates, alcohol, benzodiazepines, barbiturates
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Psychological dependence
- includes feelings of satisfaction and a desire to repeat the drug experience or to avoid discontent of not having it
- anticipation of effect powerful factor in chronic use of psychoactive drugs
- may be the only reason for intense craving and compulsive use
- leads to using drug in larger amounts, more frequentlyl or over a longer period of time
- involves giving up social, occupational or recreational activities because of drug use
- drugs causing strong psychological dependence include: cocaine, amphetamines
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What is tolerance?
- not addiction
- occurs when an increasingly larger dose of drug is required to achieve the same physiological effect
- decreased effectiveness of a drug due to its continued administration
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What is withdrawal?
physiological and/or psychological response a person experiences when a drug is no longer administered
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Signs of substance abuse
- disorganization
- frequent absences
- socially withdrawn
- slurred speech
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Drug testing
- provides evidence that an individual has used or has been exposed to a drug
- does not indicate pattern of drug use or degree or dependency
- blood screening
- blood testing
- urine testing
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Reasons for drug abuse
- experimentation
- peer pressure
- produce a desirable effect
- seeking to escape from reality/relief from conflict
- altered state of mind
- filling a void/boredom
- feelings of inadequacy/depression
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Five types of pathophysiological changes
- debilitating physical changes (malnutrition, dehydration, hypovitaminosis)
- respiratory diseases (pneumonia, pulmonary emboli, lung abscesses)
- systemic infections (endocarditits, HIV, sepsis)
- localized infections (cellulitis, sclerosis, skin abscesses)
- overdosing
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Five groups of commonly abused substances
- opiates
- cocaine
- cannabis
- hallucinogens
- inhalants
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