Griffith's experiments showing the transformation of R strain pnemococcus bacteria to S strain pnemococcus bacteria in the presence of heat-killed S strain bacteria provided evidence that
A.
Experiments by Avery, MacLeod, and McCarty supported DNA as the genetic material by showing that
D.
Hershey and Chase used radioactive 35S and 32 P in experiments to provide eveidence that DNA is the genetic material. These experiments pointed to DNA because
E.
Chargaff observed that the amount of __________ was roughly equal to the amount of ________ in all tested organisms
D.
Watson and Crick's model allowed them to visualize
E.
A fundamental requirement for the functioning of genetic material is that it must be
A.
Evidence of the semiconservative nature of DNA replication came from
B.
The primary function of DNA polymerase is to
C.
When the lagging daughter strand of DNA is synthesized, unreplicated gaps are formed on teh parental DNA. Lagging strand synthesis fills these gaps by
E.
RNA primers are necessary in DNA synthesis because
B.
Proofreading and repair occur
E.
30% of the bases in a sample of DNA extracted from eukaryotic cells are adenine. What percentage of cytosine is present in this DNA?
C.
Which of the following represents a bond between a purine and a pyrimidine (in the correct order)?
B.
Which of the following statements about DNA replication is false?
D.
The PCR technique
A.
Which of the following would not be found in a DNA molecule?
B.
If a high concentration of a particular nucleotide lackign a hydroxyl group at the 3' end is added to a PCR reaction,
A.
Meselson and Stahl were trying to determine if DNA replication was semiconservation, conservative, or dispersive by labeling E. coli DNA with a regimen of heavy nitrogen (H) for one round of replication and then transferring these cells to light nitrogen (L) for two more rounds of replication. Which of the following statements would not be true within the context of this experiment?
E. if DNA replication were semiconserative, a higher proportion of DNA molecules from future divisions would have been low density (L-L)
B.
The telomeres at the ends of linear chromosomes allow
B.
Transcription in prokaryotic cells
A.
Which of the following statements about RNA polymerase is false?
E.
Translation of mRNA into protein occurs in a _______ direction, and from ________ terminus to _________ terminus
C.
If codons were read two bases at a time instead of 3 bases at a time, how many different possible amino acids could be specified?
D.
Translate the following mRNA:
3'-GAUGGUUUUAAAGUA-5'
D.
What would happen if a mutation occurred in DNA such that the second codon of the resulting mRNA was changed from UGG to UAG?
D.
If the follwoing synthetic RNA were added to a test tube containing all the components necessary for protein translation to occur, what would the amino acid sequence be?
5'-AUAUAUAUAUAU-3'
B.
What part of the tRNA base-pairs with the codon in the mRNA?
E.
Peptidyl transferase is an
E.
Termination of translation requires...
B.
If the DNA encoding a nuclear signal sequence were placed in the gene for a cytoplasmic protein, the protein would
B.
Auxotrophs are mutant strains that
E.
The central dogma of molecular biology states that _______ is transcribed into _______, which is (are) translated into ______.
E.
A gene product can be
E.
The enzyme that catalyzes the synthesis of RNA is
E.
A mutation occurs such that a spliceosome cannot remove one of the introns in a gene. What effect will this have on that gene?
E.
Evolution occurs at the level of
B.
Natural selection acts on
B.
Which of the following statements about Mendelian populations is false?
C.
In comparing several populations of the same species, the population with the greatest genetic variation would have the
B.
The ability to taste the chemical PTC is determined in humans by a dominant allele T, with tasters having the genotypes Tt or TT and nontasters having tt. If 36% of the members of a population can't taste PTC, then according to the Hardy-Weinberg rule, the frequency of the T allele should be
E.
A gene in humans has 2 alleles, M and N, that code for different surface proteins on red blood cells. If you know that the frequency of allele M is 0.2, according to the H-W rule, the frequency of the genotype MN in the population should be
C.
If the frequency of allele b in a gene pool is 0.2 , and the population is in H-W equilibrium, the expected frequency of the genotype bbbb in a tetraploid (4n) plant species would be
A.
Random genetic drift would probably have its greatest effect on
D.
Allele frequencies for a gene locus are least likely to be significantly changed by
B.
Which of the following evolutionary agents would produce nonrandom changes in the genetic structure of a population?
E.
Suppose that a particular species of flowering plant that lives only one year can produce red, white, or pink blossoms, depending on its genotype. Biologists studying a population of this species count 300 red, 500 white, and 800 pink plants in a population. When a census of the population is taken the following year, 600 red, 900 white, and 1000 pink plants are observed. Which color has the highest fitness?
C.
In areas of Africa in which malaria is prevalent, many human populations exist in which the allele that produces sickle-cell disease and the allele for normal red blood cells occur at constant frequencies, despite the fact that sickle-cell diseaes frequently causes death at an early age. This phenomenon is an example of
B.
Which of the following is not a disadvantage of sexual reproduction?
D.
Genetic variation within a population may be maintained by
E.
Which of the following can act as a constraint on teh evolutionary process?
