BioChem Gluconeogenesis

Where does gluconeogenesis primarily occur?
- Liver
- kidney
- brain
what is the net cost of GNG per pyruvate?

6 ATP
What are the three main substrates of gluconeogenesis?
- Glycerol
- Lactate
- Alpha keto acids
What is the enzyme that bypasses Hexokinase?

Glucose-6-Phosphatase
What is the enzyme that bypasses PFK?

Fructose-1,6-bisphosphatase
What two enzymes bypass pyruvate kinase?
- Pyruvate carboxylase
- PEP carboxykinase (PEP-CK)
What enzyme is used to convert pyruvate to oxaloacetate and what is lost?
- Pyruvate carboxylase
- lose 1 ATP per Pyruvate
What enzyme is used to convert oxaloacetate to PEP? What is lost?
- PEP-carboxy kinase
- lose 1 GTP per pyruvate
What enzyme is used to convert fructose-1,6-bisphosphate to fructose-6-phosphate?

Fructose-1,6-bisphosphatase
What enzyme is used to convert glucose-6-phosphate to glucose?

glucose-6-phosphatase
How many ATP equivelent are lost during gluconeogenesis per glucose molecule gained?

12 ATP equi

Author

bradley.knox

182512

Card Set

BioChem Gluconeogenesis

Description

gluconeogenesis

Updated

2012-11-09T01:29:23Z