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How does HBV cause hepatocellular carcinoma
Integrates in DNA ->
increases insulin-like growth factor II and receptor
suppress p53
asthma diagnosis
Respiratory symptoms with normal CXR
occasional sputum eosinophils
decreased FEV1
Histo of extrahepatic biliray atresia
intrahepatic bile duct proliferation
portal tract edema and fibrosis
parenchymal cholestasis
What mutation is responsible for hypertrophic cardiomyopathy
mutations in cardiac sarcomere proteins (B myosin heavy chain)
Consequence of cholestasis that causes osteomalacia
decrease absorption of fat soluble vitamins
Where does small cell carcinoma originate from and what does it stain
From primitive cells of basal layer of bronchial epithelium
Stain neuroendocrine
:
specific enolase
chromogranin
synaptophysin
What is cerbral amyloid angiopathy
B amyloid deposit in the vessels that makes the arteries weak and prone to rupture causing more local effects than hypertension encephalopathy
How do you protect an infant from tetanus
Immunizing the mother so that IgG antibodies go to the baby
What is kinesin
ATP dependent anterograde transporter of neurotransmitter contained vesicles
What supplies the area that results in fluent aphasia
This is Wernickes area which supplied by the MCA
Treatment for AIDS patient that presents with ring enhancing lesions bilaterally in the frotnal lobe
Toxoplasmosis
TX
: pyramethamine and sulfadiazine
AIDS w/ EBV presents with
primary CNS lymphoma that consists of B cells
Fragile X presentation
Mental retardation
long face
macroorchidism
mitral valve prolapse
short stature
Support in patient communication
express concern independent of understanding
E 4 of Apolipoprotein E leads to
late familial Alzheimers
How does Methylmalonyl CoA become Succinyl CoA
via methylmalonyl CoA isomerase and vitamin B12
Where do schwennomas occur
cerebellopontine angle between cerebellum and lateral pons
Contains synaptophysin
presynaptic vesicles of neurons, neuroendocrine and neuroectoderm cells
neurons only stain synaptophysin not GFAP
UMN presentation
Spastic paralysis,
hyperreflexia
upgoing plantar reflex
Syringomyelia
Loss of pain and temperature
LMN signs
UMN signs
Polyhydramnios
increase AFP because of impaired swallowing due to abdominal atresia and anencephaly
Vitamin E deficiency
degeneration of spinocerebellar tracts,
dorsal column of spinal cord
peripheral nerves
What is bartonella henselae responsible for
Bacillary angiomatosis
culture negative endocarditis
Segmented viruses that can undergo shifts
orthomyxovirus
rotavirus
Diphenhydramine
H1 receptor antagonist with anticholinergic effects
What decreases lung compliance
pulmonary fibrosis
insufficient surfactant
pulmonary edema
EBV causes
Burkitt lymphoma
Nasopharyngeal carcinoma
CNS lymphoma in HIV
post transplant lymphoproliferative disease
mononucleosisi
Histo of chronic Hep B
finely granular and eosinophilic = gound glass
WHat sensory pathway does not go through thalamus
Olfactory tract
Skin rash of Borrelia burgdorferi
erythema chronicum migrans = red lesion with central clearing
A1AT deficiency presnentation
Seen in patients < 50 yoa that have chronic bronchitis or emphysema
history of neonatal hepatitis with cholestasis
Tay Sachs presentation
macrocephaly
ok until 2-6 months -> progressive weakness, hypotonia, abnormal startle response
Prolong loud noise damages what
hearing loss due to damage og stereocilia cells of Organ of Corti
Eczematous dermatitis histo
Spongiosis - edema that can tear desmosomes apart
GVHD
graft T cells against host skin liver and GI tract
Dubin Johnson dx
normal liver enzymes
conugated bilirubin > 50%
increased urinary coproporphyrin
What causes lacunar infarcts
Hypertensive arteriolosclerosis
Primidone
anticonvulsant that gets broken down to phenobarbital and PEMA
Entacapone MOA
inhbits peripheral methylation of l-dopa
Treatment for Cryptococcus meningitis
TX: Amphotericin B & Flucytosine
Prevention: Fluconazole
Meningococcal pili
Used for epithelial attachment to nasopharynx
Altruism
guilty feelings alleviated through selfless service
Opiate withdrawal
Abdominal pain
nausea/ vomiting
diarrhea
pilorection
pupillary dilation
fever
Cerebral aqueduct
3rd or 4th ventricle
Frederich Ataxia
Spinocerebellar tract
dorsal column
kyphoscoliosis
hypertrophic cardiomyopathy
Increased ESR and tongue pain during meals
temporal arteritis
Fragile X
Mental retardation
dysmorphic facial features
macroorchidism
Menieres Disease
increase volume of endolymph->
tinnitus
vertigo
hearing loss
Halothane toxicity
widespread centrilobular hepatic necrosis
Paraneoplastic cerebellar degeneration origin
Autoimmune antibody formation from cancer such as lung cancer
Zellweger syndrome
Peroxisomes are absent or deficit -> cant break down LCFA
Author
lazzsant
ID
181985
Card Set
Review 5
Description
Review 5
Updated
2012-11-07T12:42:57Z
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