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Benadryl & Phenylephrine Nasal Spray
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Generic name for Benadryl?
diphenhydramine HCL
What is the brand name for Benadryl?
Benadryl
What is the class for Benadryl?
Antihistamine
Anticholinergic
What is the mechanism of action for Benadryl?
Antihistamine
Blocks H
1
histamine receptors in CNS, blood vessels, respiratory and GI tracts
Drowsiness
Decreased capillary permeability
Decreased respiratory mucouse production
Decreased stomach motility / nausea
Vasoconstriction
Anticholinergic
Decreased CNS
Decreases re-uptake of dopamine in CNS
Reverses extrapyrimidal reactions
What are the indications and field use for Benadryl?
Allergic reaction
Anaphylaxis
Why - Blocks H
1
histamine receptors decreasing capillary permeability & itching
Extrapyrimidal reactions
Why - Anticholinergic in CNS decreasing activity and re-uptake of dopamine
Dosage for Benadryl?
Doseage is via slow IV push or IM
Adult
Anaphylaxis or Extrapyrimidal reactions
Benadryl 50mg slow IV push or IM
Allergic reaction with itching
Benadryl 25mg slow IV push or IM
Contraindications for Benadryl?
Known hypersensitivity or allergy
Acute asthma attack
Narrow-angle glaucoma (relative)
Drug interactions for Benadryl?
Increased effect with other CNS depressants
MAOI prolong/intensify anticholinergic effects
Side effects for Benadryl?
Paradoxical CNS excitation
Arryhthmias
Nausea / Vomiting
Decreased level of consciousness
Anaphylaxis
Seizures
Hypotension
Onset of Action for Benadryl?
IV - 5-10 minutes
AZ drug box supply for Benadryl?
2 x Benadryl 50mg in 1cc vial or prefilled syringe
Generic name for Phenylephrine Nasal Spray?
phenylephrine nasal spray 0.5%
Brand name for Phenylephrine Nasal Spray?
Neo-synephrine Nasal Spray 0.5%
Class for Phenylephrine Nasal Spray?
Topical vasoconstrictor
Mechanism of action for Phenylephrine Nasal Spray?
Vasoconstrictor
Stimulates
a
receptors in the blood vessels of the nasal mucosa which causes constriction which decreases the risk of nasal bleeding
What are the indications and field use for Phenylephrine Nasal Spray?
Faciliation of nasal intubation
Why - stimulates
a
receptors which constricts blood vessels of the nasal mucosa
Dosage of for Phenylephrine Nasal Spray?
Mucosal - spray into each nostril
Adult - 2-4 sprays in each nostril before attempting tube insertion
Contraindications for Phenylephrine Nasal Spray?
Known hypersensitivity / allergy
Drug interactions for Phenylephrine Nasal Spray?
None
Side effects for Phenylephrine Nasal Spray?
Rare with single dose, rarely absorbed systemically from nasal instillation
Hypertension
Tremors
Onset of action for Phenylephrine Nasal Spray?
Seconds
Peak effect for Phenylephrine Nasal Spray?
30 minutes
Duration of action for Phenylephrine Nasal Spray?
30 minutes to 4 hours
AZ drug box supply for Phenylephrine Nasal Spray?
1-2 bottles 0.5% 15ml bottle
Author
cjl410
ID
181877
Card Set
Benadryl & Phenylephrine Nasal Spray
Description
Phoenix College Paramedic 2012 2013 Drug Profiles - Benadryl & Phenylephrine Nasal Spray
Updated
2012-11-05T21:56:46Z
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