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Composition:
- 2 Kidneys
- 2 ureters
- bladder
- urethra
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function
- maintains internal balance or homeostasis
- formation of urine
- removal of nit waste and toxins (protein metabolism)
- water balance-- excretes or conserves water
- electrolyte balance- regulates excretion of electrolytes
- acid base balance- Hydrogen- conserve bicarbonate
- Regulation of BP- meds
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where are the kidneys located
- behind peritoneum.
- Right-- lower
- Left-- higher
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structure os kidneys
- 4" long
- 2" wide
- 1" thick
- no boney protection
- bean shaped
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protection of kidney
- adipose capsule-- fat
- renal fascia-- connective tissue
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hilum of kidney
- notched area- medial surface
- blood vessels, nerves, ureter enter.
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Internal Renal Cortex
- outer layer of the kidney
- Bowman's capsule
- proximal convoluted tubules
- distal convoluted tubule
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Internal Renal medulla
- inner portion of the kidney
- pyramids- collecting tubules and loop of Henle
- base- face the cortex
- papillae- tip or apex
- drain into calyx
- triangular shaped
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internal renal pelvis
expansion of the upper end of the ureter-- leaves the kidney
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internal Calyces
divisions of the renal pelvis
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microscopic structure-- nephron
functional units of the kidney that filter the waste products from the blood and form urine. (cleans)
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glomerulus
cluster of tiny blood vessels/capillaries
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Bowman's capsule
encloses the glomerulus
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afferent arteriole
- brings blood into the glomerulus
- larger than efferent
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efferent arteriole
- carries away remaning blood
- branches into peritubular capillaries
- smaller than afferent
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renal tubule or convoluted tubule
- proximal convoluted tubule
- loop of Henle
- distal convulted tubule becomes collecting tubule, drains into caylce and renal pelvis.
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peritubular capillaries
rise off eff arteriole, wind around conv tubule
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Route of blood thru nephron
- Renal Artery- blood with waste
- Afferent Arteriole
- Glomerulus
- Efferent Arteriole
- Peritubular Capillaries
- Renal Vein
- IVC
- recirculates in body
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Route of urine/filtrate thru nephron
- Bowman's capsule
- Prox. Convoluted Tubule
- Loop of Henle
- Distal Conv tubule
- Collecting tubule
- renal pyramids
- Renal Pelvis
- Ureter
- Urinary Bladder
- Urethra
- excreted as urine
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formation of urine through filtration
glmoerulus blood pressure causes water and dissolved sub to filter out of the blood into Bow. cap-- nephric filtrate
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formation of urine through reabsorbtion
- movement of sub out of the renal tubules into the blood in the peritubular cap
- water- osmosis- 99%
- sodium- active transport
- glucose- 100%
- back to blood
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formation of urine through secretion
- movement of sub into the urine to form the blood in the peritubular cap.
- Hydrogen- active transport
- K- active transport
- ammonia(NH3)- diffusion
- drug
- all go to conv tubule, into urine
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aldosterone
- from adrenal cortex
- increase absorption of Na and water
- decrease urine volume
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ADH
- from post pit glad
- increase reabsorption of water
- decrease urine
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ANH
- decrease Na and water resorption
- increase urine volume
- from atria
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oliguria
less than 30 ml of urine
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polyuria
large amt of urine
-
blood pressure regulator
- group of specialized cells near nephron sensitive to BP changes
- ADH
- ANH
- RBC formation- erythropoietin- secretion hormone
- activation of Vit D- calcitrol- potent form of vit D
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juxtaglomerular complex or apparatus-- renin angiotensin-- aldosterone systen
increase BP activates
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ureters
narrow tube extending from the reanl pelvis to bladder
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bladder
- reservoir where urine is stored
- transitional epithlium
- rugae- folds
- trigone- floor
- Detrusor Muscle
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urethra
- tube through which urine passes outide
- longer in men- reproductive function
- short in women increase risk for uti
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urine characteristics
- 1500-2000 ml excreted daily
- clear, amber, or straw color
- specific gravity- 1.001-1.035
- sterile
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urine composition
- water
- nit waste
- excessive material- vits...
- toxins- meds
- hormones
- yellow pigment
- abnormal components
- RBC
- glucose
- WBS/pus
- casts
- albumin
- may see in small amts-- normal
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micturition
release of urine from the body
-
regulatory sphincters
- involuntary- internal
- voluntary- external
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emptying reflex
stretch reflex at 350 ml urine bladder walls constrict
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age related changes
- loss of functional nephron units
- loss of kidney weight
- nerve transmission impaired
- decrease bladder capacity
- urinary retention
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