Cardiology I

  1. Class: I ;Sodium channel blocker
    Subclass: IA
    Prototype: Quinidine (Quinidex)
    Action: prolong refractory period; decrease automaticity and contractility

    Indications: Atrial arrhythmia; Long term use: Not For CODE

    Side Effects: wide QRS, anticholinergic, cinhonism, GI upset, low platelets

    Nursing Implications: give 1-2 hours after meals, check levels, no grapefruit juice, increases dig toxicity
  2. Class: I; Sodium Channel Blockers
    Subclass: IB
    Prototype: Lidocaine (Xylocaine)
    Action: decreases action potential, cardiac only

    Indications: Ventricular Arrhythmias; ESP. Acute

    Side Effects: Sedation, seizures = toxicity

    Nursing Implications: IV dose must be on pump, first pass effect
  3. Class: I ;Sodium Channel Blocker
    Subclass: IC
    Prototype: Propferone (Rhythmol)
    Action: Slows depolarization and conduction

    Indications: Ventricular Arrhythmias, long term

    Side Effects: vertigo, metallic taste, constipation, heart block

    Nursing implications: take with food
  4. Class: II
    Subclass: Beta Blockers
    Prototype: Atenolol (Terormin)
    Action: cardio selective, blocks beta 1 receptors

    Indications: Ventricular Arrhythmias, long term

    Side Effects: decrease HR and BP, bronchoconstriction

    Nursing Implications: Avoid in asthma and COPD, check apical pulse need grater than 60
  5. Class: III; potassium channel blocker
    Subclass: antifib
    Prototype: amiodarone (Cordarone)
    Action: Prolongs refractory periods and action potential

    Indications: recurrent life threatening Arrhythmias, v-tach

    Side Effects: pulmonary toxicity; blue gray skin; corneal microdepisits, photo sensitivity, long half life

    Nursing implications: watch for pulmonary problems, stay out of sun, 75% will experience symptoms
  6. Class: IV
    Subclass: calcium channel blocker
    Prototype: Verapamil (Calandra)
    Action: Blocks influx of Ca+ into cells

    Indications: SVTs, Slows vent rate in A-fib or A-flutter

    Side Effects: hypotension, constipation, peripheral edema, palps, tachy, Brady, Dyspnea

    Nursing implications: increases intake of H2O and fiber, limit caffeine, monitor edema
  7. Class: Other
    Subclass: misc
    Prototype: adenosine (Adenocard)
    Action: inhibits SA and AV node, impulse conduction

    Indications: SVT work as a chemical defibrillator

    Side Effects: Heart block, flushing, SOB, few seconds of asystole

    Nursing Implications: need MD present; Emergency equip available
Card Set
Cardiology I
Cardiovascular system drugs