Neuro wk2 -Polio Rabies.txt

  1. Poliomyelitis
    • Affects the motor neurons of the Medulla oblongata, pons, and spinal cord
    • highly prevalent in the 1940s and 1950s
    • today is virtually eliminatied form western hemisphere
  2. Casues of Polio
    • Enterviral infrection spread by human waster
    • replicates in oropharyngeal and intestinal mucosea
    • absorbed into blood
    • spreads to internal organs and lymph nodes
  3. two possible outcomes of Polio
    • asymptomatic or mild febrile undifferentiated illness (nonparalytic)
    • spreads to spinal cord and brainstem causing paralysis (paralytic)
  4. Symptoms of Polio
    • Stiff neck
    • red sore throat
    • gastrointestinal disturbance
  5. Treatment for Polio
    • Stalk (injection) vaccine - inactive polio virus
    • Sabin (oral) vaccine - attenuated polio virus
  6. Post-polio syndrome
    • Affects polio surviors 20 to 30 years after onset of diease
    • incidence estimated at 25% to 40% of polio surviors
    • includes excessive fatigue, muslcel weakness and or muscle joint pain
    • not preventable or curable
  7. Rabies
    • Zoonotic diseas (transmitted from animals to humans) causing encephalomyelitis (swelling of the brain and spinal cord)
    • transmitted by secretions (saliva, urine) of an infected animal bite where skin is broken
    • may become airborne
    • Incubation 10days to 7 days depending (avg 3-7 weeks)
  8. Symptoms of Rabies
    • fever
    • pain
    • mental derangment
    • rage
    • convulsions
    • paralysis
  9. Course of Rabies infection
    • attacks brainstem control of muscles for brething and swallowing
    • profuse sticky saliva
    • hydrophobia
    • death
  10. Treatment of rabbies
    • Rabies vaccine - antibody response ( 5injections over 14 days)
    • Human rabies immunoglobin - fast acting passive immunity injected directly in ot wound and at a distal intrmuscular site
Card Set
Neuro wk2 -Polio Rabies.txt
Neuro wk2 -Polio Rabies.txt