Pharmacology Final

Home

Get App

Create

Insulin Lispro
- Ultra Short Acting Insulin
- 15-30 min onset
- 1-2 hour max
- 4-6 hour duration
Regular Insulin
- Short Acting Insulin
- 30-60 min onset
- 2-3 hour max
- 6-8 hour duration
NPH Insulin
- Intermediate Acting Insulin
- 2-4 hour onset
- 4-6 hour max
- 14-18 hour duration
Insulin Glargin
- Long Acting Insulin
- delayed onset with a long-term effect (24 hours)
Pramlintide
- A synthetic Amylin
- -decreases gastric mobility
- -decreases appetite
- -lowers glucagon secretion
Metformin
- Increases the hepatic response to insulin
- the first choice drug to increase insulin response
- cannot produce hypoglycemia
Rosiglitazone/Pioglitazone
- Promotes insulin induced glucose uptake
- often used with meformin
- produces edema (not safe for bad heart)
- doesn't produce hypoglycemia
Glimepiride
- increases insulin secretion (used for type 2 w/ decreased insulin production)
- a sulfonylurea (sufa drug)--> sulfa allergy
- chronic use will develop a tolerance
- may produce hypoglycemia (via insulin)
Repaglinide
- increases insulin secretion (used for type 2 w/ decreased insulin production)
- shorter duration and faster onset then Glimepiride
- taken before meals
- used primarily when Glimepiride is not effective
- may produce hypoglycemia (via insulin)
Exanatide
- increases insulin secretion and liver response (a drop in glycogenolysis and gluconeogenesis)
- an incretin mimetic
- must be injected
- may produce hypoglycemia (via insulin)
Sitagliptin
- increases insulin secretion and liver response (a drop in glycogenolysis and gluconeogenesis)
- increases incretin levels by preventing breakdown (inhibits DPP-4)
- may be taken orally
- may produce hypoglycemia (via insulin)
Acarbose
- prevents oligosaccharide breakdown in GI by inhibiting intestinal enzyme
- less carbohydrates entering body --> lower systemic glucose
- produces gas

Author

Anonymous

18071

Card Set

Pharmacology Final

Description

Drugs to Know

Updated

2010-05-06T05:38:36Z

Show Answers