Antiarrhythmics (6 points) - pathopharm II exam 3

  1. What is the classification of lidocaine?
    Class IB - has little or no effect on HR
  2. Which antiarrhythmic is indicated in the acute treatment of ventricular arrhythmias?
  3. Which antiarrhythmic causes the following side effects: 
    Drowsiness, seizures, respiratory depression, cardiac arrest, confusion, hypotension
  4. Which antiarrhythmic causes cardiac depression and toxicity when given with Dilatin, quidinine, pronestyl, or inderal?
  5. What are the actions of lidocaine? 
    o Suppresses the automaticity of conduction tissue and spontaneous depolarization of the ventricles during diastole by altering the flux of Na+ ions across the cell membrane. 

    o Has little of no effect on heart rate.
  6. Lidocaine is contraindicated in ... 
    Advanced AV block. 
  7. Which class of antiarrhythmics is Pronestyl? 
    • Class IA
    • o   Suppresses automaticity and ventricular ectopy. 
    • o   Decreases myocardial excitability,
    • o   Slows conduction velocity,
    • o   May depress  myocardial contractility.
  8. Which antiarrhythmic is used to treat a wide variety of ventricular and atrial arrhythmias?
    Pronestyl, Quinidine, 
  9. Which antiarrhythmic is used to maintain NSR after conversion of A fib and flutter? 
  10. What are the contraindications of Pronestyl? 
    AV block and MG
  11. Which antiarrythmic causes the following side effects: 
    FUO (fever of undertermined origin) 
    SLE (systemic lupus erythematous),
    Ventricular arrhythmias - asystole,
    heart block, agranulocytosis, leukopenia, thrombocytopenia, NV, rash
  12. Which drug causes hypotension when given IV push? 
  13. What is the classification of Inderal ? 
    • Beta Adrenergic blocker, antiarrhythmic- Class II 
    • o   Blocks beta 1 and beta 2 receptor sites, decreases the heart rate  - negative chronotropic,
    • o   decreases the AV conduction - negative dromotropic 
    • o   decreases contractility - negative inotropic.
  14. Which drug is indicated in supraventricular tachycardia (SVT)? 
  15. Which drug is used in the treatment of symptoms associated with mitral valve prolapse (MVP)? 
  16. Which drug may mask the symptoms of hypoglycemia? 
  17. Which drug can cause the side effects pulmonary edema, blurred vision, raynaud's phenomenon, hyperglycemia and hypoglycemia? 
  18. Which drug's effects may increase when taken with Cimetidine? 
  19. What is the class and actions of Quinidine? 
    • Class: Antiarrhythimic - Class IA
    • o   Decreases myocardial excitability, slows conduction velocity, suppression of arrhythmias.
  20. Which drug is used in the maintanence of NSR after electrical conversion (cardioversion)? 
  21. Which drug causes the following side effects:
    vertigo, thrombocytopenia, anemia, tinnitus, arrhythmias, diplopia
  22. Which drug should not be taken with grapefruit juice, fruit juice or vitamin C? 
  23. What is the classification and actions of Amiodarone?
    • Classification: Antiarrhythmic- Type III
    • o   Prolongs the action potential and refractory period in myocardial tissue. 
    • o   Inhibits adrenergic stimulation  
    • o   Decreases automaticity
    • o   slows the sinus rate
    • o    increases the PR and the QT intervals 
    • o   decreases peripheral vascular resistance.
    • o    Suppression of ventricular arrhythmias.  
    • Has both alpha and beta adrenergenic blocking properties
  24. Which drug is used in the long-term management of life threatening ventricular arrhythmias unresponsive to conventional therapy with less toxic agents?
  25. Which drug is used in long-term management of ventricular (VT) and supraventricular tachycardia (SVT)?
  26. Which drug is good for clients with decreased ejection fractions?
  27. Which drug is a good alternative to lidocaine?
  28. Which drug causes the following side effects: 
    CHF, photosensitivity, conreal microdeposists, hypo/hyperthyroidism, pulmonary fibrosis, progressive dyspnea, blue-grey skin, tremors
  29. Which drug has an extremely long duration of action and effects may continue for a long time after it is discontinued?
  30. When taking amiodarone you should monitor:
    pulmonary, liver, thyroid and vision
  31. What are the actions of adenosine?
    • o Exerts its negative chronotropic (heart rate) and negative dromotropic (conduction) effects on the SA and the AV nodes. 
    • Actions: 
    • o   Restores NSR by interrupting reentrant pathways in the AV node. 
    • o   Slows conduction time through the AV node. Very short half-life  less than 5 seconds.
  32. Which drug is converts SVT, ST to NSR -when vagal maneuvers are unsuccessful?
    • Adenosine
    • *observe EKG expect asystole prior to restoration of NSR
  33. Which drug is used as a noninvasive diagnosis of CAD with a thallium scan stress test.
  34. Which drug should be used cautiously with asthma?
  35. Which drug should only be used in emergency and is given IV push as quickly as possible
  36. Which drug can cause CHB when client already has a preexisting AV block or 2 degree block and asystole?
Card Set
Antiarrhythmics (6 points) - pathopharm II exam 3
Antiarrhythmics (6 points) - pathopharm II exam 3