Micro Vectors

Francisella Tularensis

Transmitted by milk, undulating fever, intense back pain, headache, weakness malaise, lasts months to years

disease of childhood, often fatal, droplet transmission

Respiratory Transmission, meningitis in children, severe sequelae

Chancroid on gentials

Vanginal infection, part of normal flora, clue cells

Lipid content of cell wall up to 40%, Acid fast Staining 

Cause of Tuberculosis, no capsule, aerobic, very resistant to drying and chemicals

Glycolipids found ONLY in acid fast bacteria that are composed of mycolic acid and a large fatty acid, bound to a carbohydrate, attached to a peptidoglycan layer

Mycoside formed by the union of two mycolic acids with a disaccharide (only in virulent strains)

Mycosides the resemble cord factor with sulfates attached to the disaccharide

complicated mycoside that acts as an adjuvant that activates delayed hypersensitivity rxn in the host

mostly human disease, droplet transmission, bacteria inhaled, activated microphages attack bacteria, lung tissue becomes damaged and local necrosis of lung tissue occurs

Relative to Tuberculosis, what is the foci of the infection called?

What kind of necrosis takes place with tuberculosis?

what is the name of the entire tuberculosis infection structure? 

TB in many organ systems or just one?

how would you reactivate TB?

What kind of TB is when the tubercles are disseminated around the whole body in blood?

this kind of bacteria causes delayed hypersensitivity immune responses

When does induration not occur during TB testing?

This type of bacteria can be found in tap water, fresh and ocean water, mik, BIRD DROPPINGS, soil, and house dust...   usually infects birds and HIV patients

This is the bactria responsible for leprosy, what are the two types?

Leprosy w/ defective cellular immunity, infects every organ, primarily skin, nose, testes, and nerves (thickened)

Leprosy that is less severe, where patients can actually put up an immune response, loss of sensation in patches

Treatment for TB

Bacteria that act like fungi

This type of actinomycetes is not part of normal flora, gives TB like illness

3 types of spirochetes

what stage of syphillis is considered "the great imitator"?

tertiary symptoms of Syphillis?

imparied vision, notched teeth and impaired hearing = what?

Blueberry muffin rash is indictive of what?

Yaws - identical to T. Pallidum

Trench mouth

Large spirochete

Relapsing fever, transmitted by body lice, lesions on internal organs

Lyme disease, transmitted by deer ticks in the nymph stage

three stages of lyme disease

Spirochete hooked on each end, penetrate mucous membranes and invade blood --> other organs, also called Weil's Disease

Very Pleomorphic, tiniest free living organisms capable of self replicating, chol. for growth

Self-limiting bronchitis and pneumonia, PAP or Walking pneumonia

T-Strain Mycoplasma, found in urine, sexually transmitted

Obligate intracellular parasites, needs cell for rare materials to sythesize ATP, Gram - coccobacilli, grown in chick embryo egg sacks

Two Groups of Rickettsial Dz, what are they??

Vectored by lice, also called Rickettsia prowazeki, macular rash, brill-zinsser Dz

Vectored by flea, also called rickettsia typhi, smiliar path as epidemic typhus, not as severe

Vectored by larva of mites "chiggers" also called orientia tsutsugamushi, maculopapular rash

Vectored by spotted wood tick, maculopapular rash --> palms --> all over body, also called rickettsia rickettsii

vectored by mites, similar to chicken pox, also called rickettsia akari

vectored by lice pediculous humanus, high fevers --> 105 deg. Stays high for 5 - 6, then reoccurs, also called rickettsia quintana

The Dz has on vector, lives in ticks and cattle feces, infects endospore style, also called coxiella burnetii

what obligate intracellular parasite, gram -,  has the following life cycle??


Elementary  body (EB) is infective,
EB enters columnar epithelial cell via endocytosis
EB transforms inside cell to larger reticulate body
Reticulate body in cell divides and new elementary bodies are released

this is the leading cause of preventable blindess worldwide, aka Trachoma, only in humans, chronic conjunctivitis, can lead of PID in women

this causes psittacosis "parrot fever" very pneumonia like, when humans inhale bacteria from feathers or feces

Aeorbic gram - microbe caused outbreak of pneumonia at an american legion, facultative intracellular parasite,  found in natural and artificial water environments,  aerosolized contaminated water is route in --> infection