-
antagonistic
acting in opposition; matually opposing
-
electrolytes
Mineral salts (sodium, potassium, and calcium) that carry electrical charge in solution
-
glucagon
Hormone produced by pancreatic alpha cells that increases the blood glucose level by stimulating the liver to change stored glycogen (a starch form of sugar) to glucose
-
glucose
Simple sugar that is the end product of carbohydrated digestion
-
homeostasis
relative constancy or balance in the internal enviroment of the body, maintained by processes of feedback and adjustment in respone to external or internal changes
-
hormones
chemical substances produced by specialized cells of the body that are released slowly in minute amounts directly into the bloodstream
-
insulin
hormone produced by pancreatic beta cells that acts to remove sugar (glucose) from the blood by promoting its storage in tissues as carbohydrates (glycogen)
-
sympathomimetic
- agent that mimics the effects of the sympathetic nervous system
- (ie. epinephrine and norepinephrine)
-
target
structure, organ, tissue to which something is directed
-
another name for anterior pituitary hormones
adenohypophysis
-
Adrenocorticotropic hormone (ACTH)
- anterior pituitary hormone
- targets adrenal cortex
- promotes secretions of some hormones by adrenal cortex, especially cortisol
- Disorders: Hypersecretion causes Cushing Disease
-
follicle-stimulating hormone (FSH)
- anterior pituitary hormone
- targets ovaries and testes
- in females, stimulates egg production; increase secretion of estrogen
- in males, stimulates sperm production
- Disorders: Hyposection causes failure of sexual maturation
-
growth hormone (GH) or somatotropin
- anterior pituitary hormone
- targets bone, cartilage, liver, muscle, and other tissues
- stimulates somatic growth; increases use of fats for energy
- Disorders: hyposecretion in children causes pituitary dwarfism; hypersecrertion in children causes gigantism and in adults causes acromegaly
-
Leutinizing hormone (LH)
- anterior pituitary hormone
- targets ovaries and testes
- in females, promotes ovulation; stimulates production of estrogen and progesterone
- in males, promotes secretion of testosterone
- Disorders: Hyposecretion causes failure of sexual maturation
-
Prolactin
- anterior pituitary hormone
- targets breast
- in conjunction with other hormones, promotes lactation
- Disorders: hypersecretion in nursing mothers cause galactorrhea
-
Thyroid-stimulating hormone (TSH)
- anterior pituitary hormone
- targets thyroid gland
- stimulates secretion of thyroid hormone
- Disorders: hyposecretion in infants cause cretinism and in adults causes myxedema; hypersecretion causes Graves disease (indicated by exophthalamos)
-
antidiuretic hormone (ADH)
- posterior pituitary hormone
- targets kidney
- increases water reabsorption (water returns to the blood)
- Disorders: hyposecretion causes diabetes insipidus; hypersecretion causes syndrome of inappropriate antidiurectic hormone (SIADH)
-
Oxytocin
- posterior pituitary hormone
- targets uterus and breast
- stimulates uterine contractions; initiates labor; promotes milk secretion from the mammary glands
- Disorders: unknown
-
Calcitonin
- thyroid hormone
- regulates calcium levels in the blood in conjunction with parathyroid hormone; secreted when calcium levels in the blood are high in order to maintain homeostasis
- Disorders: most significant effects are exerted in childhood when bones are growing and changing dramatically in mass size and shape; at best, calcitonin is a weak hypicalcemic agent in adults
-
Thyroxine (T4) and triiodothyronine (T3)
- thyroid hormonesincreases energy production from all food types; increases rate of protein synthesis
- Disorders: hyposecretion in infants causes cretinism and in adults causes myxedema; hypersecretion causes Graves disease (indicated by exophthalmos)
-
parathyroid hormone (PTH)
- targets bones, kidneys, small intestine
- increases the reabsorption of calcium and phosphate from bone to blood; increases calcium absorption and phosphate excretion; increases absorption of calcium and phosphate
- Disorders: Hyposecretion causes tetany; hypersecretion causes osteitis fibrosa cystica
-
Glucocorticoids (mainly cortisol)
- adrenal cortex hormone
- targets body cells
- promote gluconeogenesis; regulate metabolism of carbohydrates, proteins, and fats; and help depress inflammatory and immune respones
- Disorders: hypo-addison disease; hyper - cushing syndrome
-
Mineralocorticoids (mainly aldosterone)
- adrenal cortex hormone
- targets kidneys
- increases blood levels of sodium and decrease blood levels of potassium in the kidneys
- disorders: hypo-addison disease; hyper - aldosteronism
-
sex hormones
- adrenal cortex hormone
- in females, possibly responsible for female libido and source of estrogen after menopause
- Disorders: Hypersecretion of androgen in females leads to virilism and of estrogen and progestin secretion in males lead to feminization
-
Epinephrine and Norepinephrine
- adrenal medullary hormones
- sympathetic nervous system target organs
- hormone effects sympathomimetic activation, increase metabolic rate and heart rate, and raise blood pressure by promoting vasoconstriction
- disorders: hypersecretion causes prolonged fight or flight reaction and hypertension
-
Glucagon (hormone)
- pancreatic hormone
- targets liver and blood
- raises blood glucose level by accelerating conversion of glycogen into glucose in the liver and other nutrients in the liver and releasing glucose into blood
- Disorders: persistently low blood glucose levels - hypoglycemia
-
Insulin (hormone)
- pancreatic hormone
- target tissue cells
- lowers blood glucose level by accelerating glucose transport into cells and the use of that glucose for energy production
- Disorders: hypo - causes diabetes mellitus; hyper - hyperinsulinism
-
adren/o, adrenal/o
adrenal glands
-
-
-
gluc/o, glyc/o, glycos/o
sugar, sweetness
-
-
kal/i
potasium (an electrolyte)
-
-
parathyroid/o
parathyroid glands
-
-
thyr/o, thyroid/o
thyroid gland
-
-
-
-
-gen
producing, forming, origin
-
-
-
-
-
acromegaly
chronic metabolic disorder characterized by a gradual, marked enlargement and thickening of the bones of the face and jaw
-
diuresis
increased formation and secretion of urine
-
glucose
simple sugar that is the end product of carbohydrate digestion
-
glycosuria
presence of glucose in the urine or abnormal amount of sugar in the urine
-
Graves disease
multisystem autoimmune disorder characterizd by pronounced hyperthyroidism usually associated with enlarged thyroid gland and exophthalmos
-
hirsutism
excessive distribution of body hair, especially in women
-
hypercalcemia
excessive amount of calcium in the blood
-
hyperkalemia
excessive amount of potassium in the blood
-
hypervolemia
abnormal increase in the volume of circulation fluid (plasma) in the body
-
hyponatremia
abnormal condition of low sodium in the blood
-
natr
sodium (an electrolyte)
-
insulinoma
tumor of the islets of Langerhans of the pancreas
-
obesity
excessive accumulation of fat that exceeds the body's skeletal and physical standards, usually an increase of 20 percent or more above ideal body weight
-
morbid obesity
body mass index (BMI) of 40 or greater, which is generally 100 or more pounds over ideal body wight
-
panhypopituitarism
total pituitary impairment that brings about a progressive and general loss of hormonal activity
-
pheochromocytoma
small chromaffin cell tumor, usually located in the adrenal medulla
-
thyroid storm
crisis of uncontrolled hyperthyroidism caused by the release into the bloodstream of increased amount of thyroid hormone; also called thyroid crisis or thyrotoxic crisis
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virile
masculine or having characteristics of a man
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virilism
masculinization in a woman or development of male secondary sex characteristics in the woman
-
protein-blood iodine (PBI)
test that measures the concentration of thyroxine in a blood sample
-
thyroid function test (TFT)
test that detects an increase or decrease in thyroid function
-
total calcium
test that measures calcium to detect bone and parathyroid disorders
-
exophthalmometry
test that measures the degree of forward displacement of the eyeball (exophthalmos) as seen in Graves disease
-
-
fasting blood glucose (GTT)
test that measures the body's ability to metabolize carbohydrates by administering a standard dose of glucose and measuring glucose levels in the blood and urine at regular intervals
-
insulin tolerance test
test that determines insulin levels in serum (blood) by administering insulin and measuring blood glucose levels in blood at regular intervals
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computed tomography
imaging techinque that rotates an x-ray emitter around the area to be scanned and measures the intensity of transmitted rays from different angles
-
Magnetic resonance imaging (MRI)
noninvasive imaging technique that uses radio waves and a strong magnetic field rather than an xray beam to produce multiplanar cross-sectional images
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radioactive iodine uptake (RAIU)
administration of radioactive iodine (RAI) orally or intravenously (IV) as a tracer to test how quickly the thyroid gland takes up (uptake) iodine from the blood
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thyroid scan
after injection of a radioactive substance, a scanner detects radioactivity and visualizes the thyroid gland
-
microneurosurgery of the pituitary gland
microdissection of a tumor using a bionocular surgical microscope for magnification
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parathyroidectomy
excision of one or more of the parathyroid glands, usually to control hyperparathyroidism
-
pinealectomy
removalo of the pineal body
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thymectomy
excision of the thymus gland
-
thyroidectomy
excision of the thyroid gland
- partial: method of choice for removing a fibrous, nodular thyroid
- subtotal: removal of most of the thyroid to relieve hyperthyroidism
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antidiuretics
- reduce or control excretion of urnine
- generic name: vasopressin (Pitressin, Pressyn)
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antithyroids
- treat hyperthyroidism by impeding the formation of T3 and T4 hormone
- Generic names: methimazole (Tapazole) and strong iodine solution (Lugol's solution)
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corticosteroids
- replace hormones lost in adrenal insufficiency (addison disease)
- Generic names: cortisone (Cortisone acetate) and hydrocortisone (A-Hydrocort, Cortef)
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growth hormone replacements
- increase skeletal growth in children and growth hormone deficiencies in adults
- Generic name: somatropin (recombinant), Humatrope, Norditropin
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insulins
- lower blood glucose by promoting its entrance into body cells and converting glucose to glycogen
- generic names: regular insulin (Humulin R, Novolin R) and NPH insulin (Humulin N, Novolin N, Humulin)
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oral antidiabetics
- treat type 2 diabetes, mellitus by stimulating the pancreas to produce more insulin and decrease peripjeral resistance to insulin
- generic names: glipizide (Glucotrol, Glucotrol XL) and glyburide (DiaBeta, Glynase)
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thyroid supplements
- replace or supplement thyroid hormones
- generic names: levothyroxine (Levo-T, Levoxyl, Synthyroid) and liothryonine (Cytomel, Triostat)
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appendage
any body part attached to a main structure
-
articulation
place of union between two or more bones; also called joint
-
cancellous
spongy or porous structure, as found at the ends of long bones
-
cruciate ligaments
ligaments that cross each other forming an X within the notch between the femoral condyles
-
-
-ate
having the form of; possesing
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hematopoiesis
production and development of blood cells, normally in the bone marrow
-
-poiesis
formation, production
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adduction
moves closer to the midline
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abduction
moves away from the midline
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Flexion
decreases the angle of a joint
-
extension
increases the angle of a joint
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rotation
moves a bone around its own axis
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pronation
turns the palm down
-
supination
turns the palm up
-
inversion
moves the sole of the foot inward
-
eversion
moves the sole of the foot outward
-
dorsiflexion
elevates the foot
-
plantar flexion
lowers the foot (points the toes)
-
Nonarticulating surfaces
- projections
- bone marking: trochanter
- very large, irregularly shaped process found only on the femur
-
sites of muscle and ligament attachment
- projections
- bone marking: tubercle, tuberosity
- tubercle - small, rounded process
- tuberosity - large, rounded process
-
Projections that form joints
- articulating surfaces
- bone marking: see below
- condyle - rounded, articulating knob
- head - prominent, rounded, articulating end of a bone
-
sites for blood vessel, nerve, and duct passage
- depressions and openings
- bone marking: see below
- foramen- rounded opening thru and nerves a bone to accomodate blood vessels
- fissure-narrow, slitlike opening
- meatus-opening or passage into a bone
- sinus-cavity or hollow space in a bone
-
The main function of the musculoskeletal system...
is to provide support, protection, and movement of body parts
-
The main function of the endocrine system...
is to secrete hormones that have a diverse effect on cells, tissues, organs and organ systems
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ankyl/o
stiffness; bent, crooked
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lamin/o
lamina (part of vertebral arch)
-
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-osis
abnormal condition; increase (used primarily with blood cells)
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myel/o
bone marrow; spinal cord
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-
-
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-
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acromi/o
acromion (projection of scapula)
-
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calcane/o
calcaneum (heel bone)
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carp/o
carpus (wrist bone)
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-ptosis
prolapse, downward displacement
-
-
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clavicul/o
clacicle (collar bone)
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-
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femor/o
femur (thigh bone)
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fibul/o
fibula (smaller bone of lower leg)
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humer/o
humerus (upper arm bone)
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ili/o
ilium (lateral, flaring portion of hip bone)
-
ischi/o
ischium (lower portion of hip bone)
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lumb/o
loins (lower back)
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metacarp/o
metacarpus (hand bones)
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metatars/o
metatarsus (foot bones)
-
-
patell/o
patella (kneecap)
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phalang/o
phalanges (bones of the finger and toes)
-
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pub/o
pelvis bone (anterior part of pelvic bone)
-
-
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spondyl/o, vertebr/o
vertebrae (backbone)
-
-
stern/o
sternum (breastbone)
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tibi/o
tibia (larger bone of lower leg)
-
leiomy/o
smooth muscle (visveral)
-
-
rhabd/o
rod-shaped (striated)
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rhabdomy/o
rod-shaped (striated) muscle
-
-
fasci/o
band, fascia (fibrous membrane supporting and separating muscles)
-
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synov/o
synovial membrane, synovial fluid
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ten/o, tend/o, tendin/o
tendon
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-desis
binding, fixation (of a bone or joint)
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-asthenia
weakness, debility
-
-
-clasia
to break; surgical fracture
-
-
-
-
-
-scopy
visual examination
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dys-
painful; bad; difficult
-
-
supra-
above; excessive; superior
-
-trophy
development, nourishment
-
syn-
union, together, joined
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ankylosis
stiffening and immobility of a joint as a result of disease, trauma, surgery, or abnormal bone fusion
-
carpal tunnel syndrome (CTS)
painful condition resulting from compression of the median nerve within the carpal tunnel (wrist canal thru which the flexor tendons and the median nerve pass)
-
claudication
lameness, limping
-
contracture
fibrosis of connective tissue in the skin, fascia, muscle, or joint capsule that prevents normal mobility of the related tissue or joint
-
crepitation
dry, grating sound or sensation caused by bone ends rubbing together, indicating a fracture or joint destruction
-
electromyography
use of electrical stimulation to record the strength of muscle contraction
-
exacerbation
increase in severity of a disease or any of its symptoms
-
ganglion cyst
tumor of tendon sheath or joint capsule, commonly found in the wrist
-
hemarthrosis
effusion of blood into a joint cavity
-
hypotoia
loss of muscular tone or a diminished resistance to passive stretching
-
-
multiple myeloma
primary malignant tumor that infiltrates the bone and red bone marrow
-
myel
bone marrow; spinal cord
-
osteophyte
bony outgrowth that occasionally develops on the vertebra and may exert pressue on the spinal cord also called bone spur
-
phantom limb
perceived sensation, following amputation of a limb, that the limb still exists
-
prosthesis
replacement of a missing part by an artificial substitute, such as artificial extermity
-
rickets
form of osteomalacia in children caused by vitamin D deficiency; also called rachitis
-
sequestrum
fragment of necrosed bone that has become separated from surrounding tissue
-
-
-
spondylolisthesis
any slipping (subluxation) of a vertebra from its normal position in relationship to the one beneath it
-
spondyl/o
vertebrae (backbone)
-
-
spondylosis
degeneration of the cervical, thoracic, and lumbar vertebrae and related tissues
-
sprain
tearing of ligament tissue that may be slight, moderate, or complete
-
strain
to exert physical force in a manner that may result in injury, usually muscular
-
subluxation
partial or incomplete dislocation
-
talipes equinovarus
congenital deformity of one or both feet in which the foot is pulled downward and laterally to the side; also called clubfoot
-
arthrography
series of radiographs taken after injection of contrast material into a joint cavity, especially the knee or shoulder, to outline the contour of the joint
-
bone density tests
radiographic procedures that use low-energy x-ray abosrption to measure bone mineral density (BMD)
-
discography
radiological examination of the intervertebral disk structures by injecting a constrast medium
-
lumbosacral spinal radiography
radiography of the 5 lumbar vertebrae and the fused sacral vertebrae, including anteroposterior, lateral, and oblique views of the lower spine
-
myelography
radiography of the spinal cord after injection of a contrast medium to identify and study spinal distortions caused by tumors, cysts, herniated intervertebral disks, or other lesions
-
scintigraphy
nuclear medicine procedure that visualizes various tissues and organs after administration of a radionuclide
-
bone
scintigraphy procedure in which radionuclide is injected intravenously and taken up into the bone
-
reduction
procedure that restores a bone to its normal position
-
closed reduction
reduction procedure where fractured bones are realigned by manipulation rather than surgery
-
open reduction
reduction procedure that treats bone fractures by placing the bones in their proper position using surgery
-
casting
application of a solid, stiff dressing formed with plaster of Paris or other material to a body part to immobilze it during the healing process
-
splinting
application of an orthopedic device to an injured body part for immobilization, stabilization, and protection during the healing process
-
traction
use of weights and pulleys to align or immobilize a fracture and facilitate the healing process
-
amputation
partial or complete removal of an extremity due to trauma or circulatory disease
-
arhtrocentesis
puncture of a joint space usig a needle to remove accumulated fluid
-
-centesis
surgical puncture
-
arthroclasia
surgical breaking of an ankylosed joint to provide movement
-
arthroscopy
visual examination of the interior of a joint and its structures using a thin, flexible fiberoptic scope called an arthroscope that contains a magnifying lens, fiberoptic light, and miniature camera that projects images on a monitor
-
bone grafting
implanting or transplanting bone tissue from another part of the body or from another person to serve as replacement for damaged or missing bone tissue
-
bursectomy
excision of bursa (padlike sac or cavity found in connective tissue, usually in the vicinity of joints)
-
laminectomy
excision of the posterior arch of a vertebra
-
lamin
lamina - part of vertebral arch
-
revision surgery
surgery repeated to correct problems of a previously unsuccessful surgery or to replace a worn out prothesis
-
bone revsion surgery
revision surgery are often required to correct abnormalities due to bone infection, or to correct misalignments of bones, broken prosthesis, and fractures of the bone around the prostheses
-
sequestrectomy
excision of a sequestrum (segement of necrosed bone)
-
synovectomy
excision of a synovial membrane
-
-
synov
synovial membrane, synovial fluid
-
total hip replacement (THR)
surgical procedure to replace a hip joint damaged by a degenerative disease, commonly arthritis
-
calcium supplements
- treat and prevent hypocalcemia
- (ie. calcium carbonate, calcium citrate)
-
gold salts
- treat rheumatoid arthritis by inhibiting activity within the immune system
- (ie. auranofin, aurothioglucose)
-
nonsteroidal anti-inflammatory drugs (NSAIDs)
- decrease pain and suppress inflammation
- (ie. ibuprofen, naproxen)
-
salicylates
- Relieve mild to moderate pain and reduce inflammation
- (ie. aspirin, magnesium salicylate)
-
skeletal muscle relaxants
- relieve muscle spasms and stiffness
- (ie. cyclobenzaprine, methocarbamol and aspirin)
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