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Side Scatter measures?
Forward Scatter measures?
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Impedence
Obstruction through an electrical field, can measure size of cell
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Anemia
Decreased RBC mass
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MCH
MCHC
Mean Cell Hb= Hb/ RBC count
Mean Cell Hb Concentration = Hb/ MCV
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Iron Deficiency
- Low MCH, Low MCHC
- Small, pale RBCs
- Most common nutritional disorder worldwide
- Low ferritin, High transferrin (TIBC)
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Anisocytosis
- Variation in RBC size
- Seen in thalassemia
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Poikilocytosis
- Variation in RBC shape
- Seen in thalassemia
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Plummer-Vinson Syndrome
- Esophageal web, atrophic glossitis, strawberry tongue
- Associated with Iron Deficiency Anemia
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Thalassemia has
Target cells, crew cut skull
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Macrocytic Anemias
Folate Deficiency (hypersegmented neutrophils, Normal methylmalonic acid)
- B12 Defieciency (Pernicious Anemia due to destruction of parietal cells that produce intrinsic factor.)
- Dietary deficiency is rare
- Subacute combined degeneration of spinal cord, increased methylmalonic acid
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