-
Categories of Hypertension
- <120, <80 = Normal
- 120-139, 80-89 = Prehypertensive
- 140-159, 90-99 = Stage 1 HTN
- >160, >100 = Stage 2 HTN
-
Hypertension in Diabetes?
>130, >80
-
Contemporary Antihypertensive Drug Classes & Targets
- Diuretics (Kidney): Thiazides, Aldosterone Antagonists
- Sympathetic Nervous System Inhibitors: Adrenoreceptor Blockers (B-Blockers, a1-blockers, a1/B-Blockers), Centrally Active Agents, Adrenergic Neuron Blockers
- Renin-Angiotensin Inhibitors: ACE Inhibitors (ACEIs), Angiotensin Receptor (AT1) Blockers (ARBs), Renin Inhibitor
- Ca2+ Channel Blockers
- Direct Arterial Vasodilators
- Hypertensive Crisis: Nitroprusside, Diazoxide, Fenoldopam
-
Drugs Used for Less Selectivity: Often Monotherapy
- Diuretics
- B-Adrenoreceptor Antagonists
- ACE Inhibitors/ AR Blockers
- Ca2+ Channel Blockers
-
Diuretics
- Thiazide: Hydrochlorothiazide (chlorthalidone, metolazone, indapamide)
- Adosterone Antagonists/ Potassium Sparing: Spironolactone, Eplerenone
- Loop Diuretics
- Furosemide
|
|
