Mid-term Meds

  1. Name the 6 classifications of respiratory meds?
    • antihistamines
    • decongestants
    • antitussives
    • expectorants
    • bronchodilators
    • non bronchodilating respiratory drugs
  2. _____s, MOA prevents: vasodilation, increased GI, respiratory, salivary and lacrimal secretions.  Prevents capillary permiability. 
    antihistamine (histamine antagonist)
  3. Give 3 examples of non sedating antihistamines.  2 examples of traditional antihistamines. 
    • loratadine (Claritin)
    • fexofenadine (Allegra)
    • Cetirazine (Zyrtec)

    • diphenhydramine (Benadryl)
    • chlorpheniramine (Chlor-Trimeton)
  4. H1 receptors act on?

    H2 receptors act on? 
    • H1: smooth muscle contraction.  ex bronchioles
    • H2: Mediate secretions.  Increased hr, GI secretions
  5. Nasal deongestants can be broken down into 3 categories?
    • adrenergics (sympathomimetics)
    • anticholinergics (parasympatholytics)
    • topical corticosteroids
  6. ________s, MOA: (intranasal), local vasoconstriction of dilated arterioles, reduce blood flow and nasal congestion (PO) above + increase airway patency.  
  7. One example of an intranasal adrenergic.  One example of a PO adrenergic?
    Intranasal: oxymetazoline (Afrin, Dristan, Neo-Synephrine)

    PO: pseudophedrine hydrochloride- PO (Sudafed, Dimetapp)
  8. ________'s, MOA: block acetylcholine receptors; when applied locally, inhibits secretions from the serous and seromucous glands lining the nasal mucosa. 
  9. One example of an anticholinergic med?
    ipratropium (Atrovent).

  10. ________'s, MOA limits the inflammatory response elicited by antigens?
  11. 3 examples of Corticosteroids?
    • fluticasone (Flonase)
    • budesonide (Rhinocort)
    • beclomethasone (Beconase)
  12. _____'s MOA: supress the cough reflex.
  13. 2 examples of opioid antitussives?

    3 examples of non-opioid antitussives?
    • Opioid: codeine (or hydrocodone syrups)
    •              Robitussin A-C

    • Non-opioid: dextromethorphan
    •                     Robitussin DM, Vicks Formual 44
    •                      benzonatate

    *Tessalon Perles(C)?*
  14. ________s, MOA thins secretions and allows for coughing them up?
  15. 1 example of an expectorant?
    guaifenesin (Mucinex)
  16. 3 categories of bronchodilators?
    • Beta-Adrenergic Agonists
    • Anticholinergics
    • Xanthine Derivatives
  17. ________s MOA: dilate bronchioles by stimulating the beta2 adrenergic receptors in the lungs?
    Beta-Adrenergic Agonists
  18. Give 5 examples of Bronchodilators/Beta-Adrenergic Agonists?
    • albuterol (Ventolin)
    • levalbuterol (Xopenex) Beta 2
    • metaproternol (Alupent) Beta 2
    • salmeterol (Serevent) Beta1/Beta2
    • epinephrine (Adrenalin) Alpha/Beta Beta1/Beta2
  19. _________s MOA: Competes for cholinergic receptors on bronchial smooth muscle, inhibiting vagal tone?
  20. 2 examples of anticholinergics?
    • ipratropium bromide (Atrovent)
    • tiotropium (Spiriva) dry powder inhaler
  21. Side effects of anticholinergics?  Slude?
    • Salivation
    • Lacrimation
    • Urination
    • Diarrhea
    • Emesis (increased GI motility)
  22. ________s MOA: act directly on the smooth muscle to dilate the bronchi?
    Xanthine Derivatives
  23. 2 examples of Xanthine Derivatives?
    • theophylline (Theodur) PO, rectal, inj, topical
    • Aminophylline inhalation/IV
  24. 3 examples of non-bronchodilating respiratory drugs?
    • Leukotriene Receptor Antagonists
    • Corticosteroids
    • Mast Cell Stabilizers
  25. _______s MOA: Competative receptor antagonist of leukotriene receptors?
    Leukotriene Receptor Antagonists
  26. 3 examples of Leukotriene Receptor Antagonists?
    • montelukast (Singulair) PO
    • zafirlukast (Accolate) oral
    • zileuton (Zyflo) oral
  27. _________s, MOA: have a direct effect on smooth muscle relaxation; they enhance the effect of beta adrenergic bronchodilators and inhibit inflammatory responses that may result in bronchoconstriction?
  28. 3 examples of corticosteroids?
    • budesonide phosphate (Pulmicort Turbohaler), inh
    • fluticasone (Flonase) inh
    • methylprednisolone (Solu-Medrol) iv/PO
  29. __________s, MOA: inhibits the release of histamine and other mediators of inflammation, making it an indirect anti-inflammatory agent?
    Mast cell stabalizers
  30. 2 examples of mast cell stabilizers?
    • cromolyn sodium (Intol) inh
    • nedocromil (Alocril)
Card Set
Mid-term Meds
Mid-term Meds