-
-
CI (Cardiac Index)
2.5-4.0 L/min/m2
-
-
SVI (Stroke Volume Index)
33-47 mL/beat/m2
-
SVR (Systemic Vascular Resistance)
800-1200 dynes-sec/cm-5
-
SVV (Stroke Volume Variation)
-
-
FloTrac Alogrithim
1) SVI Normal (40-50)
2) SVI Low (<40)
3) SVI High (>50)
- 1) SVI Normal (40-50) - Pressor
- 2) SVI Low (<40) - Inotrope
- 3) SVI High (>50) - Diuretic
-
Propofol Dose
5-50 mcg/kg/min titrate to effect
-
Verapamil Dose for AFIB
5-10 mg IV push over 2 min/ Max 20
-
Norepinephrine (Levophed)
0.01-5 microgram/kg/min
-
-
Vasopressin (ADH Analog)
- 0.04 unit/min (septic shock)
- 0.2-0.4 (variceal bleed)
-
Fentanyl dose
- 1-3 mcg/kg (loading dose)
- 0.7-5 mcg/kg/hr (maintainance)
-
Lasix Drip
- 40 mg over 1-2 min (loading)
- 10-40 mg/hr titrate to effect (max 160 mg/hr)
-
Insulin drip
- 0.1 units/kg (loading dose)
- 0.5-20 units/ hr (weight based, usually 0.1 units/kg/hr and titrate to effect)
-
Lorazepam (Ativan drip)
- 1-6 (loading dose)
- 0.5-15 mg/ hr (usual dose, high dose associated with metabolic acidosis)
-
Narcan (Naloxone) usual dose
- 0.4-2 mg IV q2-3min PRN
- Look for pulmonary edema
-
Amiodrone drip
- 150mg in 100ml D5W over 10 min (loading)
- 1mg/min for 6hours, then 0.5/min for 18 hours
- Then change to PO
-
Precedex
- 1mcg/kg over 10 min (loading dose)
- 0.2-1.5 mcg/hr (usual dose)
-
Dobutamine
- 2.5-20 Mcg/kg/min (usual dose)
- ------------------
- 5-15 beta 1 (contractility)
- >15 (vasodilation, Inc HR)
-
Dopamine (renal, cardiac, pressor doses)
- Renal 1-3 mcgm/kg/min
- Cardiac 3-10 mcgm/kg/min
- Pressor 10-30 mcgm/kg/min
-
Diltiazem drip
- 0.25 mg/kg over 2 min then 0.35 mg/kg over 2 min (load)
- 5-10 mg/hr (usual)
-
Vancomycin drug level
- Peak 20-40, Trough 5-10
- If peak too high > Decrease amount of each dose
- Trough too high> Decrease frequency of doses
-
Gentamicin
- Peak 6-10 mcg/ml; trough < 1 mcg/ml
- If peak too high > Decrease amount of each dose
- Trough too high> Decrease frequency of doses
-
Cortisol level
- 3-20 High in AM Low in PM
- High in stress states 20-40
- Stim Test: 0.25 ACTH IM, peak cortisol response, 30 to 60 minutes later, should exceed 18 to 20 g/dL (> 497-552 nmol/L).
-
Risk of HIV and HepB after transfusion
- HIV 1 in 1-2 million
- Hep B/C 1 in quater to half million
-
Estimation of maintainance fluid / hr by weight
- 4/2/1
- 4ml for first 10 kg
- 2 for second 10kg
- 1ml /kg thereafter
-
Normal protein/Albumin value
- protein 6-8.5
- Albumin 3.5-5.5
-
Half life
Albumin
Transferrin
Prealbumin
- Albumin- 20
- Transferrin- 10 (normal 200–400 mg/dL)
- Prealbumin- 2 (normal 20-40) <5 severe, 5-10moderate, 10-15 mild depletion
-
RQ
- 1- carbohydrate
- 0.8 protein
- 0.7 fat
-
CEA (Carcinoembryonic antigen)
- 0–2.5 ng/mL
- Increased in: Colon cancer (72%), lung cancer (76%), pancreatic cancer (91%), stomach cancer (61%), cigarette smokers, benign liver disease (acute 50% and chronic 90%), benign GI disease (peptic ulcer, pancreatitis, colitis). Elevations >20 ng/mL are generally associated with
- malignancy. For breast cancer recurrence (using 5 ng/mL cutoff), sensitivity 44.4% and specificity 95.5%.
- Monitoring after surgery: Test is used to follow progression of colon cancer after surgery (elevated CEA levels suggest recurrence 3–6 months before other clinical indicators), although such monitoring
-
-
Short Gut syndrome
In adults, 480cm normal small bowel length, <180 increase risk of SGS and <60cm (with colon) are unlikely to achieve independence from parenteral nutrition.
-
Surgical site Infection:
Clean
Clean contaminated
Contaminated
Gross Contaminated
- Clean- 2%
- Clean contaminated- 3-5%
- Contaminated 5-10%
- Gross Contaminated 30%
-
Central line infection: how many CFU?
>15 colony forming uits = line infection
-
SIRS
- Temp <36C (<96.8F)
- >38.3C (100.4F)
- RR >20 or PaCO2 <32
- HR >90
- WBC >12k or <4k or >10% band
-
SEPSIS
SIRS + long with either a culture-proven or visually identified infection
-
SEVER SEPSIS
- Severe sepsis refers to sepsis plus at least one of the following signs of hypoperfusion or organ dysfunction:
- Areas of mottled skin
- Capillary refilling requires three seconds or longer
- Urine output <0.5 mL/kg for at least one hour, or renal replacement therapy
- Lactate >2 mmol/L
- Abrupt change in mental status
- Abnormal electroencephalographic (EEG) findings
- Platelet count <100,000 platelets/mL
- Disseminated intravascular coagulation
- Acute lung injury or acute respiratory distress syndrome (ARDS)
- Cardiac dysfunction (ie, left ventricular systolic dysfunction), as defined by echocardiography or direct measurement of the cardiac index
-
Septic shock
- Septic shock exists if there is severe sepsis plus one or both of the following despite adequate resucitation:MAP <60 mmHg (or <80 mmHg if the patient has baseline hypertensionMAP >60 mmHg requires dopamine >5 mcg/kg per min, norepinephrine <0.25 mcg/kg per min, or epinephrine <0.25 mcg/kg per min .
-
Adequate fluid resuscitation:
- 20 to 30 mL/kg of starch,
- infusion of 40 to 60 mL/kg of saline solution
- PCWP 12 to 20 mmHg.
- (CVP) of 8 to 12 mmHg
-
Refractory Septic Shock
>60 mmHg (or >80 mmHg if the patient has baseline hypertension) requires dopamine >15 mcg/kg per min, norepinephrine >0.25 mcg/kg per min, or epinephrine >0.25 mcg/kg per min despite adequate fluid resuscitation
-
Epinephrine
0.1-1 mcg/kg/min (max 5)
-
Mortality rate of SIRS, sepsis, severe sepsis, and septic shock
7, 16, 20, and 46 percent, respectively
-
Indication of thoracotomy based on CTube outpu
- >1500 after initial insertion
- >250cc/hr for 3 hours
- 2500 cc/24hour
- or bleeding with instablity
|
|